英国约克大学博士后职位—造血干细胞生物学
英国约克大学博士后职位—造血干细胞生物学
约克大学(University of York),建于1963年,位于英国英格兰约克,是一所公立研究型大学。
约克大学是英国罗素大学集团、世界大学联盟、N8大学联盟、白玫瑰大学联盟和江苏—英国高水平大学联盟成员。该校校友中有15位英国议会议员。
约克大学位列2023QS世界大学排名162位,2024THE世界大学排名第147位。
Post Doctoral Researcher in Haematopoietic Stem Cell Biology
University of York
Post Doctoral Researcher in Haematopoietic Stem Cell Biology
Department
Biology
Salary
£36,024 - £44,263 per year
Grade
Grade 6
Contract status
Fixed term
Hours of work
Full-time
Based at
University of York campus
Posted Date
06/11/2023
Apply by
30/11/2023
Job Reference
12841
Documents
Job Description 12841.pdf (PDF, 192.28kb)
Role Description
We are looking for a talented and motivated full-time Postdoctoral Research Associate to join the groups of Professor Ian Hitchcock and Professor David Kent based in the Department of Biology at the University of York. The Hitchcock and Kent labs focus on understanding the mechanisms that regulate normal haematopoietic stem cell maintenance and how this is altered in haematological malignancies. The Hitchcock and Kent labs take a multi- disciplinary team science approach to understand the dynamics of HSC clonal expansion ( Nature 2018, Nature, 2022, Nature Medicine , in press) characterise and modify the mechanisms of cytokine receptor activation ( Science 2020, PNAS, 2021, Cell, 2023) and determine mechanisms responsible for the development of haematological disorders ( NEJM, 2015, Blood 2018, Science 2020).
Role
The successful candidate will work on Cancer Research UK-funded projects focused on understanding the mechanisms of oncogenic cytokine signalling in haematological malignancies and developing agents that block hyperactivity to fine-tune haematopoietic stem cell expansion and outputs.
The successful candidate will benefit from a highly collaborative programme with academic and clinical interactions in the U.K. and Europe including; Prof. Jacob Piehler (Osnabrück, Germany), Prof. Chris Garcia (Stanford, USA), Prof. Bertie Göttgens (Cambridge, UK) Prof. Alan Warren (Cambridge, UK) and Dr Peter Campbell. The post holder will also benefit from a multidisciplinary environment locally at the Centre for Blood Research.
Skills, Experience & Qualification needed
You will already possess or will soon be awarded a PhD in cell biology, haematology, immunology, cancer biology or a related subject. You will have experience in a range of cellular and molecular techniques, including; cell line and primary cell culture, flow cytometry, growth and signalling assays and in vivo models. You will need to be able to work independently as well as part of the programme team working on related projects. Excellent communication skills are essential and you should be keen to develop project/team leadership skills. The post holder will be expected to drive their independent projects, but also work closely with each other and with other lab members and assist in the identification and development of potential areas of research and the development of proposals. The post holder will be expected to write up research results for dissemination through publications, seminar and conference presentations and will be encouraged to participate in public engagement and science outreach activities. Opportunities for mentorship and additional collaborations will be available and encouraged.
The post is funded by Cancer Research UK. The post is full time, on a fixed term basis for 36 months This is a grade 6 post; £35,308 to £43,155 per year depending on experience.
Closing date: 30th November 2023
Interview date: TBC
For informal enquiries: please contact Prof. Ian Hitchcock (ian.hitchcock@york.ac.uk), Prof. David Kent (david.kent@york.ac.uk).
The University strives to be diverse and inclusive – a place where we can ALL be ourselves.
We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.
We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork
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