美国EMD公司招聘免疫肿瘤学方向博士后

Req Id 108861 - Posted 09/16/2015 - United States - Massachusetts - Billerica - Research & Development - Career Level (2) - Full-time
 

Post-Doctoral Scientists

We are seeking highly motivated scientists to join the Discovery Technologies department at EMD Serono as post-doctoral fellows. These individuals will be responsible for developing a new state-of-the-art high throughput screening platform for bispecific antibodies against targets for our Immuno-oncology platform. The Post-Doctoral fellows will evaluate and develop different technologies for bispecific antibody discovery and isolation from immunized animals, as well as production, screening and functional testing of bispecific antibodies against targets in the Immuno-oncology space. These Post-Doctoral positions will also provide opportunities to expand knowledge and experience through research in an industry setting, while addressing important scientific questions.

Two Post-Doctoral positions are available, each for 2 years with the possibility of extension.

KEY TASKS & RESPONSIBILITIES

• Design and develop new cell-based assays to select the best combination of antibodies based on evaluation of immune-stimulatory and tumor-inhibitory activities

• Evaluate and develop technologies for bispecific antibody discovery (display technology, B cell cloning, engineering), preparing libraries for display, perform selection, B cell sorting and production and screening of bispecific antibodies

• Discover therapeutic candidates with the best combinations of bispecific antibody-and-targets

• Techniques will include vector cloning and expression systems, reporter gene assay, flow cytometry, immunological assays, cell line generation

CANDIDATE’S PROFILE

EDUCATION & LANGUAGES

• Ph.D. in Immunology, Immuno-oncology, Biology, or similar related field
• Fluent in written and spoken English

PROFESSIONAL SKILLS

• Deep  knowledge of Immunology and proficiency in hands-on experimental work with immune cells and assays preferred
• Strong research experience in immunology, cellular and molecular biology, protein engineering
• Track record of independently designing, executing, troubleshooting experiments
• Experience with antibody discovery technologies (display libraries, B cell cloning) is preferred but not required
• Experience with animal handling is a plus

PERSONAL SKILLS & COMPETENCIES

• Organized, highly motivated, innovative with critical thinking and problem solving skills.
• Strong team player
• Excellent oral and written communication skills
• Ability to work in intense, fast paced, interactive work environment
• Strong sense of initiative and interest in learning new technologies and new disease-relevant biology
• Good interpersonal skills essential to effectively work with colleagues

EMD Serono is the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, a global pharmaceutical and chemical group. We strive to create value and benefit patients by transforming medical science into breakthrough solutions in our core therapeutic areas of neurodegenerative diseases, fertility and metabolic endocrinology, as well as oncology and autoimmune/inflammatory diseases as emerging areas of expertise.