法国国家科学研究中心细胞神经科学博士后职位

We seek to hire a highly motivated postdoctoral scientist to investigate the role of the synaptic microenvironment in the control of NMDA receptors, using a combination of approaches including brain slice electrophysiology, molecular replacement, optogenetics and genetically-modified mice.

The candidate should have a solid background in brain slice preparation and cellular electrophysiology (whole-cell patch-clamp). The candidate should also show strong interest in molecular and cellular neuroscience with special focus on synaptic transmission and plasticity. A background in molecular biology and receptor pharmacology would be a plus.

The project is to be developed in the team of Pierre Paoletti at the Institut de Biologie de l’Ecole Normale Supérieure (IBENS) in Paris, a team that has received international recognition for its work on the structure, function and pharmacology of NMDA type glutamate receptors (Neuron 2008, Nature 2009, Nat Rev Neurosci 2009, Nat Neuro 2011, EMBOJ 2011, Nat Struc & Mol Biol 2013, Nat Rev Neurosci 2013, PNAS 2014, Neuron 2014). The position has 2 years of initial funding, with the possibility for extension afterwards.

IBENS is a leading biology institute in Europe that gathers several world-class researchers from diverse fields including genetics and genomics, developmental biology, systems biology and neuroscience. IBENS is located in the center of Paris (Latin Quarter) in a highly stimulating and dynamic environment, close to several other top research institutions (Institut Curie, Collège de France, ESPCI Paris Tech…).