美国转译基因组学研究院博士后职位

The Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research with life changing results. TGen is focused on helping patients with cancer, neurological disorders and diabetes, through cutting edge translational research (the process of rapidly moving research towards patient benefit). TGen physicians and scientists work to unravel the genetic components of both common and rare complex diseases in adults and children. Working with collaborators in the scientific and medical communities literally worldwide, TGen makes a substantial contribution to help our patients through efficiency and effectiveness of the translational process.

Job Summary:
The Pancreatic Cancer Research Lab at TGen aims to develop novel targeted therapies for patients with advanced pancreatic cancer. We employ genomic and biochemical approaches including whole genome sequencing and tissue array immunohistochemistry to identify alterations responsible for driving the progression and/or chemoresistance of pancreatic cancer. Promising alterations are further validated for drug targeting and candidate therapies are then developed and tested in cell line and animal models. By closely working with clinicians at TGen's Clinical Service, we seek to rapidly translate laboratory findings to the clinic. Promising therapies are promptly evaluated in pilot clinical trials. Conversely, hypotheses generated by clinicians based on clinical observations are readily tested in the laboratory.