美国贝勒医学院药物发现中心博士后职位—药代动力学

美国贝勒医学院药物发现中心博士后职位—药代动力学

贝勒医学院（Baylor College of Medicine）是美国休斯敦的一所私立医药学校，被认为是全美最杰出的医学院之一，获中国教育部认证。学校在世界范围内的生物医药研究领域处于领先地位，学校最早建立于一九零零年，迄今为止已经有一百多年的悠久历史了。

贝勒医学院为学生提供财政援助和奖学金，帮助学生减轻就学期间的经济压力，符合要求的学生都可以申请奖学金和财政援助。学校致力于医药和研究生教育，并且因而获得了超过一亿美金的捐赠，是美国六十三所获得超过一亿捐赠的优秀大学之一。

Postdoctoral Associate- Pharmacokinetics

Baylor College of Medicine

Summary

The Center for Drug Discovery ( https://www.bcm.edu/research/centers/drug-discovery ) is a strategic research center at Baylor College of Medicine in Houston, Texas. We are currently seeking highly motivated, well-organized and enthusiastic Postdoctoral Fellows contributing to our research in the fields of drug metabolism and toxicity, as well as the study of chemical properties that aid in crossing the blood-testis barrier (BTB). In our well-equipped laboratory, we utilize advanced instruments such as Thermos UHPLC-Q Exactive MS, Orbitrap Exploris™ 120, Thermo Quintus (triple quadruple), and Imaging mass spectrometry (IMS, Bruker timsTOF fleX MALDI-2) to conduct LC-MS-metabolomics, pharmacokinetics, and spatial metabolomics. Understanding the drug metabolism could predict the possible adverse events of drugs in clinic and also could reduce the risk of the drug candidates in drug development. Determining chemical features passing BTB will facilitate the drug development for therapeutic targets behind BTB. Baylor College of Medicine is located in the prestigious Texas Medical Center and offers a highly interactive environment and a strong infrastructure for research and career development. To obtain further details about the positions, feel free to email Dr. Feng Li ( fl3@bcm.edu ) directly.

Job Duties

Plans, designs and conducts experiments.

Characterizes the drug metabolites using High-resolution LC-MS and NMR.

Analyzes LC-MS data from mouse tissue and plasma to evaluate their abilities for passing through BTB.

Documents and interprets experimental results and report to principal investigators.

Conducts literature searches and summarizes information in an appropriate format for a particular study.

Helps to write and prepare manuscripts.

Performs other job related duties as assigned.

Minimum Qualifications

MD or Ph.D. in Basic Science, Health Science, or a related field.

No experience required.

Preferred Qualifications

Doctoral degree in Chemistry, Drug metabolism and pharmacokinetics, Pharmacology, and Toxicology, or a related Biomedical Science discipline.

Experience in medicinal chemistry and structural characterization using LC-MS and NMR.

Skilled in the identification of drug metabolites in vitro and in vivo.

Experience in working with animals, including animal treatment and tissue collection.

Have the ability to plan, design and conduct experiments, especially on drug metabolism, tissue distribution, and metabolites identification. Pharmacology and toxicology backgrounds is a plus.

Have the experience of preparing and writing the manuscript.

Have experience in LC-MS method development and sample preparation, and data analysis

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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