美国西奈山伊坎医学院博士后—HIV-1生物学和HIV神经发病机制

美国西奈山伊坎医学院博士后—HIV-1生物学和HIV神经发病机制

西奈山伊坎医学院是纽约市的一所私立医学院，是由西奈山医院建立起来的，其主楼由著名建筑设计师I.M.Pei设计。该院在2022《美国新闻与世界报道》的医学院中研究排名17，基础医疗排名69。

该院建立之时附属于纽约城市大学；1999年改为附属于纽约大学，但没有跟纽约大学医学院合并；2007年，西奈山从纽约大学独立出来，2010年获得认证，得以独立颁发学位。

Postdoctoral fellow

Icahn School of Medicine at Mount Sinai

Job Description

Postdoctoral positions in HIV-1 biology and HIV neuropathogenesis

The Volsky lab in the Department of Medicine/Infectious Diseases at Icahn School of Medicine at Mount Sinai, New York, seeks a Virologist/HIV Specialist to study the interactions between HIV and drugs of abuse in promoting HIV neuropathogenesis and virus- and drug-related behaviors. The studies will be conducted in mice using a model of HIV neurocognitive disease by EcoHIV infection and include participation in the NIDA/NIH National Scorch consortium and related projects. The research will focus in part on the role of microglia in HIV neuropathogenesis/drug abuse and include isolation of live microglia from mouse brain for virological, gene expression, and potentially epigenetic characterization. Projects will involve exposure to state-of-the-art approaches such as the addictive substance self-administration in mice, sn/sc RNaseq, epigenetics, as well as mouse behavioral tests and molecular biology/virology techniques including HIV (EcoHIV) genome reconstruction to identify viral functions required for neuropathogenesis in vivo.

Educational requirements: A PhD, MD, or MD/PhD degree in HIV/Virology, molecular biology, or a similar field.

Additional preferred skills/experience:

-Experience in viral neuropathogenesis

-Interest in substance use disorder (SUD) research

-2-3 years of experience working with rodents, including brain dissection and analysis

-Track record of independence in research projects

-Track record in working within a team and in multi-team environments

-Good communication and interpersonal skills

-Experience with NGS data generation/analysis is a plus.

This is a 3-year position with the possibility of extension or promotion.

Applicants who meet the requirements listed above are invited to send their curriculum vitae and the names and addresses of three references to:

David J. Volsky, Ph.D.

Professor

Department of Medicine/Infectious Diseases

Icahn School of Medicine at Mt. Sinai

Annenberg Building 21-42

1 Gustave L. Levy Place

New York, NY 10029

212-241-1015 (office coordinator Ilene)

212-241-1089

david.volsky@mssm.edu

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