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Job Description
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
The Arena
The Innovative Medicines (iMed) unit for Cardiovascular and Metabolic Diseases push the boundaries of science to deliver life-changing medicines to patients suffering from Heart Failure, Diabetes or Chronic Kidney Disease.
CVMD iMed is agnostic to molecular modality and utilize small molecules, peptides, macrocycles, RNA based therapeutics etc which provides a unique opportunity to address scientific questions in an innovative way and creates a stimulating environment for you as a Medicinal Chemist.
Our pipeline and the research areas we focus on to demonstrate scientific leadership in are to a large extent driven through collaborations and gives you access to the most recent knowledge and the best experts in the world.
The Medicinal Chemistry Department is a critical player in identifying novel targets and chemical series from both traditional hit finding strategies and also phenotypic screening approaches. We need you who like to explore new scientific approaches, bridge your thinking between chemistry and biology and work in an open and collaborative environment nursing novel ideas.
The role
This is a senior scientific role within the Medicinal Chemistry department. You will be an authority in medicinal chemistry and will develop and lead the science in this field. You will have a profound impact on multiple projects across the CVMD iMed, in all phases from target selection to drug candidate selection. The role holder will also provide discipline based scientific leadership and represent the department and AstraZeneca at interdisciplinary meetings internally as well as externally. The role-holder will influence the strategy of Medicinal Chemistry towards the future needs.
Key Deliverables:
Lead the Medicinal Chemistry in projects and secure delivery of overall project objectives
Responsible together with the Med Chem Leadership Team for clear, compelling scientific strategy in the field of medicinal chemistry
Initiate, lead and champion new innovations that help the iMed deliver toward future success.
Evaluate and manage external collaborations & in-licensing opportunities
Demonstrate scientific leadership through high quality publications, conference presentations and by building networks with external scientific leading groups
Show strong leadership capabilities in collaborative working, strategic thinking and in the development of people and organization.
Experience
Ideally, you should have a Ph. D. degree in a relevant scientific discipline with 5 or more years post-doctoral research experience in medicinal chemistry and drug discovery, preferentially from an industrial setting. You will have the ability to operate effectively in a multidisciplinary matrix research environment, providing leadership and insight in medicinal chemistry. You will be recognized internationally as evidenced by your external disclosures and publication record. This role also demands in-depth collaboration skills. We seek you who have experience from leading projects or chemistry programs on projects across the drug discovery process including hit finding and late stage optimization. Your knowledge base in cell biology and assay technologies will be critical to us. Knowledge in cardiovascular and metabolic disease area will be seen as advantages.
Key qualities:
Will have a proven strong track record of innovation and milestone delivery from drug discovery projects as a Lead Medicinal Chemist.
Very good knowledge of related disciplines and interfaces, in particular biology, DMPK and assays technologies.
A highly self-motivated, scientifically critical individual capable of receiving and analyzing input from multiple disciplines and deciding on focused course of action
Good ability to lead other scientists and create commitment and engagement.
Good awareness of the competitive landscape and of industry trends.
Very good written and verbal communication skills, including presentations to senior leaders
More information
If you have any questions about this role, please contact hiring manager:
Malin Lemurell
Head of Department
CVMD iMed Medicinal Chemistry |
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