The Department of Microbiology and Immunology at the University of Miami has multiple opportunities available under the mentorship of Dr. Eli Gilboa.
Research in the Gilboa laboratory focuses on developing cell-targeted immune modulatory strategies using oligonucleotide aptamer drug and drug delivery platforms, including the development of novel high throughput sequencing-based aptamer isolation strategies.
Postdoctoral Associate - Cancer and HIV Immunotherapy #088888
Applicants with documented track record of high impact publications and extensive experimental background in preclinical cancer immunotherapy or HIV immunology studies will be considered. Experience in nucleic acid molecular biology is desirable.
Postdoctoral Associate - Oligonucleotide Aptamer Development #099999
Applicants, both at early and advanced postdoctoral stage with documented track record of extensive experimental background in advanced nucleic acid molecular biology techniques will be considered. Experience in aptamer development is desirable.
Relevant publications:
1. Pastor F, Kolonias D, Giangrande PH, Gilboa E. Induction of tumor immunity by targeted inhibition of nonsense mediated mRNA decay. Nature. 2010 465:227
2. Berezhnoy, A, Stewart, C. A., James McNamara, J., Thiel, W., Giangrande, P., Giorgio Trinchieri, G., and Gilboa, E. Isolation & optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing. Mol. Ther., 2012, 20:1242
3. Berezhnoy, A., Castro, I., Levay, A., Malek, T.R., and Gilboa, E. 2014. Aptamer-targeted inhibition of mTOR in T cell enhances antitumor immunity. J. Clin. Invest. 124:188
4. Schrand, B., Berezhnoy, Brenneman, R., Williams, A., Levay, A., Kong, L-Y, Rao G, Zhou, S., Heimberger, A. B., Gilboa, E. 2014. Targeting 4-1BB costimulation to the tumor stroma with bispecific aptamer conjugates enhances the therapeutic index of tumor immunotherapy, Can. Immunol. Res.,2:867.
Minimum requirements include a PhD or MD.
For immediate consideration, please apply online at www.careers.med.miami.edu and reference position number #088888 or #099999. Click on “Postdoctoral Opportunities” in the “Job Category” field.
The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here<http://www1.eeoc.gov/employers/upload/eeoc_self_print_poster.pdf> for additional information.
