美国布莱根和妇女医院皮肤科博士后职位

美国布莱根和妇女医院皮肤科博士后职位

布列根和妇女医院(Brigham and Women’s Hospital)由彼得·本特·布列根医院（成立于1913年）、罗伯特·布雷克·布列根医院 （成立于1914年）和波士顿妇女医院（始于1832年）于1980年合并而成。

POSTDOCTORAL FELLOWSHIP

Employer

Brigham and Women's Hospital - Department of Dermatology

Location

Boston, Massachusetts (US)

Salary

70K + depending on PGY experience plus benefits

Closing date

15 Apr 2025

The Kupper laboratory in the Department of Dermatology at Brigham and Women’s Hospital (BWH) in Boston is seeking post-doctoral fellow. We have made several fundamental advances in the characterization how the tumor microenvironment suppressed the CD8 T cell response and how to overcome the suppression.  Manipulation of cytokine activation of CD8 T cells, along with blocking cytokine activation of myeloid cell suppression, is central to our approach and relies on our ability to manipulate these molecules and their receptors in a unique way.  Along with spatial profiling and molecular imaging, we are using engineered therapeutic molecules to tip the balance towards T cell activation in the tumor microenvironment.   Our research utilizes both standard immunologic techniques (immunofluorescence/ immunohistochemistry, microscopy, flow cytometry and sorting, in situ hybridization, western blot, etc) and novel technologies (high-throughput TCR sequencing, nanostring analysis, single cell RNAseq, multispectral labeling and imaging of tissue, spatial profiling, and laser capture microscopy). We work with both human specimens and mouse models of disease.

Highly-motivated candidates with an M.D., Ph.D., or M.D./Ph.D. in Immunology or a related field are strongly encouraged to apply. Applicants should possess strong laboratory, analytical, interpersonal and communication skills.

The BWH Department of Dermatology is located in the Longwood Medical Area, which contains ten major institutions, including research-oriented hospitals, research institutes, Harvard Medical School, and the Harvard School of Public Health, providing a rich training environment. Interested candidates should email a brief cover letter indicating their research interests and career goals, CV, and contact information for 3 references to:

Thomas Kupper, M.D.

Brigham and Women’s Hospital

Department of Dermatology

77 Ave. Louis Pasteur, HIM660

Boston, MA 02115

Attn:  Matthew Opperman; MOPPERMAN@BWH.HARVARD.EDU

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