美国伊利诺伊大学芝加哥分校博士后职位—表观遗传学

美国伊利诺伊大学芝加哥分校博士后职位—表观遗传学

伊利诺伊大学芝加哥分校（University of Illinois Chicago），简称UIC，创立于1982年，公立研究型大学，卡内基基金会认证的一类美国国家级研究型大学之一，超过3.4亿美元的科研经费使它稳居美国研究经费排名前50，是芝加哥地区规模最大、综合实力最强的公立大学。

Postdoc Research Associate - Thomas Lab

University of Illinois Chicago

Job Description

UIC is among the nation’s preeminent urban public research universities, a Carnegie RU/VH research institution, and the largest university in Chicago. UIC serves over 34,000 students, comprising one of the most diverse student bodies in the nation and is designated as a Minority Serving Institution (MSI), an Asian American and Native American Pacific Islander Serving Institution (AANAPSI) and a Hispanic Serving Institution (HSI). Through its 16 colleges, UIC produces nationally and internationally recognized multidisciplinary academic programs in concert with civic, corporate and community partners worldwide, including a full complement of health sciences colleges. By emphasizing cutting-edge and transformational research along with a commitment to the success of all students, UIC embodies the dynamic, vibrant and engaged urban university. Recent “Best Colleges” rankings published by U.S. News & World Report, found UIC climbed up in its rankings among top public schools in the nation and among all national universities. UIC has over 300,000 alumni, and is one of the largest employers in the city of Chicago.

The University of Illinois Chicago offers a very competitive benefits portfolio. Click for a complete list of Employee Benefits.

An NIH-funded Postdoctoral Research Associate position is available in the laboratory of Dr. Douglas Thomas at the University of Illinois Chicago. This position is open immediately to investigate redox-based mechanisms of epigenetic regulation in diseases.

The Thomas Lab focuses on exploring novel mechanisms of epigenetic gene regulation through a combination of biochemistry, cell biology, and genomics approaches. Our research employs both in vitro and in vivo models, integrating advanced methodologies such as mass spectrometry, confocal microscopy, electron paramagnetic resonance imaging of free radicals, chemiluminescence, electrochemical analyses, genomic, and molecular biology techniques.

Notably, we have identified the free radical signaling molecule nitric oxide (NO) as an endogenous regulator of epigenetics, capable of influencing mRNA, histone, and DNA methylation. Current projects emphasize genome-wide analyses of epigenetic events contributing to the development and treatment of epigenetic-driven diseases. These projects build on our recent work, including studies on mRNA methylation (2023) and DNA methylation (2025.

We are seeking a self-motivated, career-oriented postdoctoral researcher to explore the function and dynamic regulation of mRNA and DNA methylation. The position offers a vibrant research environment and dedicated mentoring to support your scientific and professional growth.

Duties & Responsibilities

Responsibilities include, but are not limited to:

Cell culture studies.

Cell free, kinetic and structural studies.

DNA/mRNA Sequencing

Mentoring graduate students.

Manuscript and grant writing / editing.

Record keeping of the experiments.

Presenting the results at scientific meetings.

Participate in weekly lab meetings, Journal Clubs and common seminars within the Department.

Perform other related duties and participate in special projects as assigned.

Minimum Qualifications

PhD degree in Molecular Biology, Biochemistry, or a related discipline.

Prior research lab experience.

Ability to independently design and analyze research projects, with excellent manuscript/grant writing and communication skills.

Protein and DNA/RNA handling experience.

Genome editing skills.

Preferred Qualifications

Experience with bioinformatics, genome editing, and high-throughput sequencing is highly desirable but not required.

Experience with HPLC-MS, mass spectrometry and proteomics is advantageous.

For fullest consideration, applicants should apply and upload a CV/Resume, a cover letter describing your research background and interest, and the name and contact information of three professional references to: https://uic.csod.com/ux/ats/careersite/1/home/requisition/13959?c=uic by January 31, 2025.

The University of Illinois Chicago is an affirmative action, equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status, or status as an individual with a disability.

Offers of employment by the University of Illinois may be subject to approval by the University’s Board of Trustees and are made contingent upon the candidate’s successful completion of any criminal background checks and other pre-employment assessments that may be required for the position being offered. Additional information regarding such pre-employment checks and assessments may be provided as applicable during the hiring process.

As a qualifying federal contractor, the University of Illinois System uses E-Verify to verify employment eligibility.

The University of Illinois System requires candidates selected for hire to disclose any documented finding of sexual misconduct or sexual harassment and to authorize inquiries to current and former employers regarding findings of sexual misconduct or sexual harassment. For more information, visit https://www.hr.uillinois.edu/cms/One.aspx?portalId=4292&pageId=1411899

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