美国辛辛那提儿童研究基金会博士后职位—脑癌和癌症神经科学

美国辛辛那提儿童研究基金会博士后职位—脑癌和癌症神经科学

辛辛那提儿童医学中心是一所非盈利性儿科研究型医学中心，全美排名第三。

Postdoctoral Fellow Position in Brain Cancer & Cancer Neuroscience

Cincinnati Children's Research Foundation

Job Description

A postdoctoral position is immediately available in the laboratory of Dr. Richard Lu (https://www.cincinnatichildrens.org/research/divisions/e/ex-hem/labs/lu), to study brain cancer, including glioblastoma, medulloblastoma, DIPG/DMG, and ependymoma, aiming to uncover the underlying mechanisms of tumor formation, recurrence, and metastasis. We are seeking highly driven and motivated individuals to join our dynamic research team, dedicated to advancing the understanding of therapy-resistant mechanisms, cancer epigenetics, cancer neuroscience, tumor immunology and therapy.

Research Focus

We investigate both cancer cell-intrinsic and -extrinsic factors, delving into oncogenic networks, epigenetics, metabolism, tumor microenvironment, and immune cell interactions. Our goal is to enhance the understanding of brain tumor biology and translate findings into therapeutic advancements.

Research Approaches

Our work leverages state-of-the-art methodologies and technologies including: genetically engineered mouse models; cancer genomics, single-cell multi-omics, and spatial transcriptomics; integration of high-throughput drug and Crispr/cas9 screens, and exploration of innovative therapies, such as proton therapy and experimental immunotherapeutics.

Recent Publications

Our research findings have been published in the peer-reviewed journals, including Cell (Liu, X., et al., 2024; Yu, Y., et al, 2013), Nature (Luo, Z., et al., 2022), Cancer Cell (Zhang, L. et al., 2019; Lu, F. et al., 2016; Wu et al., 2018), Nature Medicine (He, X. et al., 2018; He, X. et al., 2014), Cell Stem Cell (Weng et al., 2019), Nature Cell Biology (Hu, X., 2022), Nature Communications (Luo et al., 2023; Zhang et al., 2021; Wang et al., 2020), Science Advance (Wu, L, 2020), among others.

About Us

Our research group is based at Cincinnati Children’s Hospital, a renowned institution consistently ranked in the Honor Roll of US News’ America’s Best Children’s Hospitals. It has been named to Best Children's Hospitals Honor Roll for the 2024-25 rankings and stands at the top in all ten subspecialties.

Benefits and Opportunities

We offer a competitive compensation package. The selected Postdoctoral Fellow will have access to state-of-the-art facilities, mentorship from leading experts, and opportunities for professional development and collaboration in an exceptional research environment.

Qualifications

Candidates who have recently obtained a PhD or MD and possess a strong background in one or more of the following areas are encouraged to apply: cancer biology, neurobiology, and genomic biology. Join us in our mission to advance the understanding and treatment of brain tumors and make a lasting impact on the lives of patients and their families.

Join Us

Be part of our mission to advance the understanding and treatment of brain tumors, making a meaningful impact on the lives of patients and their families.

To Apply

Please email your current CV and the names of three references to Richard.Lu@cchmc.org.

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