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荷兰特文特大学博士后职位—工程化3D肿瘤模型

2024年04月11日
来源:知识人网整理
摘要:

荷兰特文特大学博士后职位工程化3D肿瘤模型

特文特大学(英文:University of Twente;荷文:Universiteit Twente),简称UT,曾译为屯特大学,也称特温特大学,创建于1961年,位于荷兰恩斯赫德市,是荷兰著名的研究型大学,系4TU成员、欧洲创新大学联盟(ECIU)成员。

Postdoc position in engineered 3D tumor model

University of Twente

Netherlands

May 05, 2024

Contact:N/A

Offerd Salary:€ 5.090

Location:N/A

Working address:N/A

Contract Type:Other

Working Time:Full time

Working type:N/A

Ref info:N/A

The Chair Engineered Therapeutics within Advanced Organ Bioengineering and Therapeutics group at the University of Twente has a postdoc position funded by the Dutch Cancer Foundation (KWF).

Pancreatic cancer is one of the deadliest cancer types with a dismal survival rate of only 8%. A major problem is that patients are diagnosed at late stages in which curative treatments are hardly possible. Lack of clinical samples from early stages of the cancer does not allow identify biomarkers to diagnose tumor at early stage. The project aims to develop novel engineered 3D tumor models that mimic the early stage of pancreatic tumor and identify early diagnostic biomarkers using this model and validate with clinical samples.

As a postdoctoral researcher, you will collaborate closely with a multidisciplinary team, including Amsterdam University Medical Centre and international industrial partners. Your primary goal will be to develop advanced 3D tumor models with an engineering perspective using your knowledge and expertise in biomedical engineering and lab-on-chip systems. At the same time, you will be performing sophisticated biological assays, multi-omics approaches to validate and benchmark the models and find biomarkers. This position offers a unique opportunity to make a significant impact in the early diagnostics of this deadly cancer while advancing your career in academia.

Your profile

For this position we are seeking an ambitious candidate with a doctoral degree in biomedical engineering, bioengineering, or a related field with experience in cancer biology. A solid background in developing 3D in vitro models, particularly in lab-on-chip technology, and 3D bioprinting tools is essential with a good understanding of cancer biology. Knowledge and hand-on experience in Computer Aided Design, MATLAB, bioinformatics, and biomarkers is highly appreciated. We expect to have excellent communication skills and a collaborative mindset. The candidate needs to have a strong track record of scientific writing, evidenced by peer-reviewed publications in the field. You are fluent in English and able to collaborate with external parties in regular meetings and work visits.

Our offer

·  Fulltime position for 2.5 years (or a part-time position (0.8 fte) for 3 years, to be negotiated)

·  The university offers a dynamic ecosystem with enthusiastic colleagues in a stimulating scientific environment.

·  The salary amounts, depending on education and experience, minimal € 3.877,- to a maximum of € 5.090,- gross per month in case of a fulltime employment.

·  A holiday allowance of 8% of the gross annual salary and a year-end bonus of 8.3%.

·  The number of holiday hours for full-time employment is 232 hours per calendar year.

·  Professional and personal development programmes.Information and application

Please send your application via the ‘Apply now' button, and include:

·  Your letter of motivation emphasizing your specific interest and motivation,

·  A Curriculum Vitae, including a complete list of publications, lectures and presentations at conferences and a list of third-party funding.

·  An academic transcript of master and PhD education

·  Contact information of two references

An interview and a scientific presentation will be part of the selection procedure. Please apply via the provided button below. We are an equal opportunity employer and value diversity and inclusion at our university. We encourage applications from all sections of society.

You are welcome to contact Prof. Dr. Jai Prakash (j.prakash@utwente.nl), or our secretary Ms. Karin Hendriks (aottnw@utwente.nl) for any questions you may have.

About the department

The Chair Engineered Therapeutics - Advanced Organ Bioengineering and Therapeutics embedded in the Department of Bioengineering Technologies aims to develop innovative diagnostic and therapeutic technologies designed to target a diseased organ, resulting to improved therapeutic efficacy and reduced side effects in patients. The Chair contributes to the education of the Biomedical Engineering curriculum and various other disciplines of the University of Twente by delivering various courses in the field of drug delivery, nanomedicine, and targeted therapeutics.

The research of the chair focuses on the development of advanced 3D tumor in vitro models to understand the complex biology, find diagnostic biomarkers as well as examine the therapeutic efficacy of developed therapeutics against cancer. Also, the group is working at the forefront of the drug delivery technologies, designing novel targeting technologies to modulate specific cells within the tumor microenvironment.

About the organisation

The Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.

Want to know more?Prakash, J. (Jai)

Full Professor - Engineered Therapeutics

Prakash, J. (Jai)

Full Professor - Engineered Therapeutics

Do you have questions about this vacancy? Then you can contact Jai for all substantive questions about this position and the application procedure. For general questions about working for the UT, please refer to the chatbot.

Contact

Phone:+31534893096

Email:j.prakash@utwente.nl

How to applyStep 1

Apply. When you see a vacancy that appeals to you, you can apply online. We ask you to upload a CV and motivation letter and/or list of publications. You will receive a confirmation of receipt by e-mail.

Step 2

Selection. The selection committee will review your application and you will receive a response within 2 weeks after the vacancy has been closed.

Step 3

1st interview. The 1st (online or in person) meeting serves as an introduction where we introduce ourselves to you and you to us. You may be asked to give a short presentation. This will be further explained in the invitation.

Step 4

2nd interview. In the second interview, we will further discuss the job content, your skills and your talents.

Step 5

The offer. If the conversations are positive, you will be made a suitable offer. If applicable, we will sign you up for screening.

Your Colleagues

·  Steenbergen, W. (Wiendelt)

Personal page

·  Pizzoccaro - Zilamy, M.D. (Marie-Alix)

Personal page

·  Vargas Llona, L.D. (Laura)

Personal page

·  Our mission Human Touch

At the UT it's all about people, in line with our university's High Tech Human Touch philosophy. In everything we do, the well-being and future of our students and staff are paramount. From research and teaching to personnel management, campus management and the use of new technologies.

·  Our mission We are a university of technology

Our university is a public institution that serves society. We are accountable to society for the ways in which we use our academic freedom. We are responsible for ensuring that the power of science and technology is harnessed to achieve the best possible impact in a changing world. We cherish our rich tradition of combining technical and social sciences in our five profiling themes: Improving healthcare by personalized technologies; Creating intelligent manufacturing systems; Shaping our world with smart materials; Engineering our digital society; and Engineering for a resilient world.

·  Our mission We help to strengthen society

We help society meet the challenges of today and tomorrow. But we are also transparent about what science and technology can and cannot do in finding sustainable solutions. And help translate these solutions into everyday life.

·  Our mission We are sustainable

We want our communities to flourish and show resilience, so we seize opportunities for innovation. We are knowledgeable and have an eye for what society needs. Our students and staff receive all the guidance they need in their quest for ecological, social and economic sustainability. “The University of Twente is all about people. Our sustainable technologies help to strengthen society.”

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