丹麦奥胡斯大学博士后—RNA适体用于精准皮肤病定位

丹麦奥胡斯大学博士后—RNA适体用于精准皮肤病定位

Postdoc in RNA aptamers for precision skin disease targeting

Employer

Aarhus University (AU)

Location

Aarhus, Midtjylland (DK)

Salary

Competitive

Closing date

18 Apr 2025

The interdisciplinary Nanoscience center (iNANO) at Aarhus University invites applications for a 1-year postdoc position, with the possibility of an extra year extension. This position offers an exciting opportunity to join a research project focused on developing innovative RNA aptamer therapeutics to target skin conditions, with a strong focus on Vitiligo.

The position is available from July 1st 2025 or as soon as possible hereafter.

Expected start date and duration of employment

This is a 1-year postdoc position, with the possibility of extension for an extra year, available from 1st of July or as soon possible.

Job description

You are expected to contribute to a project focused on developing chemically modified RNAs to target Langerhans cells (LCs) for Vitiligo intervention. This research involves a multifaceted approach, including: i) the generation of aptamer-drug conjugates for precise LCs targeting, ii) the in vitro selection of novel RNA aptamers, and iii) the assessment of their therapeutic potential in mouse models and human skin samples. This project is part of an international and interdisciplinary collaboration with scientists working in molecular biology, biomedicine, immunology, and dermatology.

Your profile

Applicants should hold a PhD in molecular biology, biochemistry, nanoscience, nanotechnology, or medicinal chemistry and have experience with RNA and/or nucleic acid nanotechnology. Expertise in (RNA) aptamer selection, bioconjugation strategies, immunology, primary cells, and binding/cell assays with a particular focus on FACS will be a major advantage. Experience with tissue samples, cell cultures, and mouse models will be an advantage.

The ideal candidate should be socially oriented, self-driven, and motivated, with strong communication skills and the ability to work as part of an international team. Proficiency in written and spoken English is a requirement for the position.

Who we are

iNANO, Interdisciplinary Nanoscience Center (www.inano.au.dk), was established in 2002 and at present is a major research and education center based at Aarhus University hosting 60 senior scientists, ~100 PostDocs and ~100 PhD students. The center combines expertise and faculty from Physics, Chemistry, Molecular biology and Medicine to carry out world-class interdisciplinary research in Nanoscience and Nanotechnology.

The center gives access to a broad range of infrastructure, tools and expertise including clean-room facilities. With a 5-year undergraduate nanotechnology programme and nanoscience graduate programme (https://phd.nat.au.dk/programmes/nanoscience/) the center provides a full educational environment. In addition to the large base of basic research, the center has a large number of ongoing industrial projects and partnerships.

In the Valero lab, we offer a dynamic, social and interdisciplinary scientific environment with a strong focus on nucleic acid chemistry, RNA technologies, biomedicine, and catalysis. Our team thrives in a collaborative atmosphere, working closely with leading scientists in biomedicine, virology, and synthetic biology at Aarhus University and within our international network.

What we offer

The successful applicant is offered:

Access to a well-equipped research infrastructure and collaborative access to state-of-the-art core facilities.

A scientific environment inviting open and critical thinking within and across interdisciplinary research fields, also fostering collaboration with academia and industrial partners.

A working environment with teamwork, network activities among young scientists across different faculties at Aarhus University and social activities.

A workplace characterised by professionalism, equality and a healthy work-life balance.

Place of work and area of employment

The place of work is the Interdisciplinary Nanoscience Center (iNANO),; Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C.

Contact information

Further information about the position may be obtained from Assistant Prof. Julián Valero jvalero@inano.au.dk. Interested candidates are encouraged to contact for further details about the position.

Deadline

Applications must be received no later than 18 April 2025

Application procedure

Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline. Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

If you wish to add a referee after you have submitted your application, you must send this person’s details (name, job title, place of work, and email address) as well as the name of the position you have applied for to: HR.Nattech@au.dk

Formalities and salary range

Natural Sciences refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.

The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.

Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Taxation and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities.

Salary depends on seniority as agreed between the Danish Ministry of Taxation and the Confederation of Professional Associations.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.

Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more here. Please find more information about entering and working in Denmark here.

Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it here.

At the Faculty of Natural Science at Aarhus University, we strive to support our scientific staff in their career development. We focus on competency development and career clarification and want to make your opportunities transparent. On our website, you can find information on all types of scientific positions, as well as the entry criteria we use when assessing candidates. You can also read more about how we can assist you in your career planning and development.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.

Aarhus University

Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,300 employees, and has an annual revenues of EUR 935 million. Learn more at www.international.au.dk/

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