美国宾夕法尼亚大学化学系博士后职位

美国宾夕法尼亚大学化学系博士后职位

宾夕法尼亚大学（英文：University of Pennsylvania），简称宾大（英文：UPenn, Penn），位于宾夕法尼亚州费城市，是一所私立研究型大学，常春藤盟校之一，美国大学协会创始成员，全球大学校长论坛成员。大学创建于1740年，是美国第五古老的高等教育机构，也是美国第一所从事科学技术和人文教育的现代高等学校。该校的创建者是美利坚合众国著名开国元勋之一的本杰明·富兰克林。

Postdoctoral researcher

Department of Chemistry, University of Pennsylvania

The Cooperman laboratory in the Chemistry Department of the University of Pennsylvania is seeking to recruit a postdoctoral student with a strong interest in applying biochemical and biophysical approaches to elucidate the mechanism and regulation of protein synthesis, with application to both the development of potent, nontoxic drugs to treat nonsense mutation diseases and the elucidation of how epitranscriptome modifications of mRNA, tRNA, and rRNA interact to reprogram translation during cancer development. These efforts will build on our accomplishments in developing and applying a highly purified, eukaryotic cell-free protein synthesis system, as described in several publications  (Zhang et al., Elife 2016 5:e13429; Ng et al., ACS Med Chem Lett. 2018 9:1285-1291; PNAS 2021 118, e202059911; Huang et al., Nature Comm 2022 13:2413; Ghelfi et al., Biomolecules. 2023;13(2):242) and current work. The successful applicant should be mechanistically oriented with expertise in biochemical and molecular biological approaches.   Qualifications include a recent Ph.D. in biochemistry, chemical biology, molecular biology or a related field and a strong interest in protein synthesis. Familiarity with bioinformatic tools is a plus. Applicants must have a strong work ethic, communication & organization skills, and a willingness to think about and learn new methodologies as projects evolve. Applicants should send a cover letter and CV with contact information for three references to Barry Cooperman (cooprman@pobox.upenn.edu).

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