美国克利夫兰诊所博士后职位—炎症与免疫

美国克利夫兰诊所博士后职位—炎症与免疫

克利夫兰医学中心是世界最著名医疗机构之一，机构集合医疗、研究和教育三位一体，提供专业医疗和最新治疗方案的非营利性机构。克利夫兰医学中心始建于1921年2月28日，隶属于俄亥俄州一家非营利性公司——克利夫兰临床基金会，并由其经营。

克利夫兰医学中心本部位于克利夫兰市，在佛罗里达、内华达、加拿大和阿布扎比开设有分院。克利夫兰诊所本部共有超过1400个床位，整个医院体系拥有4400个床位。

在2017-2018年度全美最佳医院排名中，克利夫兰医学中心综合排名位列全美第二，仅次于梅奥医学中心。其中心脏外科和泌尿外科为全美排名第一；普外科，风湿病以及肾脏内科位列第二；内分泌，骨科，呼吸科全美排名第三；妇产科和老年病学排名第五；神经内/外科排名全美第六；肿瘤科排名第七；眼科学排名第九。

2018年12月，世界品牌实验室编制的《2018世界品牌500强》揭晓，克利夫兰诊所排名第200。

Postdoctoral Fellow – Srinivasan Dasarathy Lab

Cleveland Clinic

Location: Cleveland, OH

Job Number: 7140058 (Ref #: ccf18162166)

Posting Date: Apr 14, 2023

Application Deadline: Open Until Filled

Job Description

Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

Principal Investigator: Srinivasan Dasarathy, MD

Lerner Research Institute Department: Inflammation and Immunity

Lab Research Topics:

·         Cell signaling

·         RNA translation

·         Biochemistry

·         Gene editing

·         Imaging

·         For more information about the lab’s research, please visit: https://www.lerner.ccf.org/immuno/dasarathy/ or contact Dr. Dasarathy at dasaras@ccf.org

Job Responsibilities:

·         Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation

·         Culture of multiple cell lines, primary cell cultures

·         Basic molecular methods (real time PCR, immunoblots)

·         Confocal microscopy, fluorescent imaging

·         mRNA translational regulation

Education:

·         PhD or MD/PhD required

·         MD with relevant laboratory experience may substitute for PhD

Languages:

·         English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

·         Previous experience in a research or academic setting.  Graduate student experience meets this requirement.

·         Scientific writing experience

Physical Requirements:

·         Ability to perform work in a stationary position for extended periods

·         Ability to operate a computer and other office equipment

·         Ability to communicate and exchange accurate information

·         Ability to distinguish color

·         Manual dexterity to handle specimens and repair equipment

·         Ability to lift and transport equipment or specimens weighing up to 20 pounds

·         May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Additional Preferred Qualities:

·         Crispr/Cas9

·         Viral delivery systems

·         Handling mouse strains (not essential)

·         Protein expression, protein-protein interaction studies

·         fraction separation, organelle isolation

·         Ability to analyze and perform mass spectrometry data for metabolites preferred but not essential.

Personal Protective Equipment:

·         PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

All application materials should be submitted directly via email to Dr. Dasarathy at dasaras@ccf.org.

·         Cover letter

·         CV

·         Contact information for 3 references

Keywords: Postdoc, Research, LRI, Crispr/Cas9, Skeletal muscle, Tissue specific deletion, Inducible vector systems, Reporter analyses, FRET/BRET, Post-translational modifications, Generate tagged constructs, Subcellular organelle studies

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