英国伦敦国王学院圣约翰皮肤病研究所研究助理职位

英国伦敦国王学院圣约翰皮肤病研究所研究助理职位

Research Associate (Dermatology)

St John's Institute of Dermatology, King's College London

An exciting position is available in the Cutaneous Immunology group led by Dr Paola Di Meglio, at St John’s Institute of Dermatology, King’s College London. The post holder will join a vibrant research group interested in the immune and environmental mechanisms underpinning pathogenesis and outcome to therapies in inflammatory skin disorders. This post will focus on studying the environmentally regulated aryl hydrocarbon receptor (AHR) pathway in psoriasis to develop novel therapeutic strategies which harness its homeostatic function.

The postholder will develop and interrogate murine and humanized in vivo models of skin inflammation, conduct in vitro and ex vivo assays to measure CYP450 enzymatic activity in human and murine specimens, and perform flow cytometric and imaging mass cytometric analysis of human and murine immune cells and tissue, liaising with clinical and academic collaborators.

The successful candidate will have a PhD in a relevant biomedical discipline, a background in immunology or pharmacology with expertise in animal models and experience in working with human primary samples and will ideally be available for an immediate start. Prior experience in skin immunology and model of skin inflammation and transplantation will be advantageous.