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以色列希伯来大学招聘分子生物学博士后

2014年08月27日
来源:知识人整理
摘要:
Postdoctoral Position : Jerusalem, Israel

The KaganovichLab (www.kaganovichlab.com) is looking to hire new postdocs and phd students to work on a range of projects at the cutting edge of investigations into the cell biology of protein folding quality control and aggregation.

We work with yeast, cell culture, and worms. We are especially interested in recruiting someone with substantial experience working with yeast. Experience in molecular biology (plasmid construction in particular) and biochemistry are also a plus.

A number of projects are running and well-funded in the lab, including yeast genetics and cell biology projects investigating the mechanism and spatial regulation of protein folding quality control and aggregation; basic cell biology of protein movement in live cells; mechanisms of aggregate toxicity and aggregate management in yeast and human cell models; stress management in neurons in a C. elegans optogenetic/single-cell cell-biological model; as well as several other projects in disease models of ALS, Parkinson’s, MJD, and Alzheimer’s.

My lab has a state-of-the-art imaging set-up in house. We have a dual resonant scanning 4ms/frame confocal system which is optimized for 4D imaging, and a TIRF/structured illumination super-resolution microscope. We are also building a single-plane illumination system which may be a project of interest for an engineering student.

Another exciting project in the lab is the study of replicative rejuvenation, or asymmetric inheritance of damage during mitosis. We have identified a new mechanism of replicative rejuvenation with implications for studying aging and differentiation.

Ideal postdoctoral candidates will have a strong publication records with at least one first author paper in a good journal, and will be candidates for external postdoctoral fellowships. If you are interested in doing a postdoc in the lab please provide letters of reference and a research proposal for a possible contribution to the main research directions of the lab….