英国剑桥大学生物信息学方向博士后职位招聘

　　Research Associate (Bioinformatician)

　　University of Cambridge - Department of Paediatrics

　　Professors David Rowitch and Lucy Raymond supervise the "Next Generation Children's Project" in Cambridge which uses whole genome sequencing to identify rare genetic disorders in the Intensive Care Setting. A major challenge is rapid delivery of actionable DNA sequence variants in a timeframe for use by the bedside clinician. This Informatics Postdoc will address these challenges in a collaborative working group comprising Medical Genetics and Informatics mentors and Clinical Neonatologists at the Addenbrooke's Cambridge University Hospital Foundation Trust.

　　We are looking for a scientist with a PhD (or equivalent) in Bioinformatics, Statistics or Computational Biology with experience in Next Generation Sequencing data analysis, in particular whole genome and RNA-seq data. The successful candidate will work on different genomic projects that involve analysis and integration of different molecular data types to study human gene variants and clinical phenotypes. Experience with analysis of data from different high-throughput experiments, such as DNA-seq data (mutation calling, copy number analysis), RNA-seq (isoform quantification and splicing detection), or ChIP-seq (peak calling, differential binding) will be valued.

　　We are a multidisciplinary team formed by clinicians, genetic councilors, computational biologists and clinical fellows, therefore a cooperative approach to working is needed for this position, as well as an ability to communicate and interact with colleagues with other backgrounds. In addition to data acquisition handling and analysis, the successful applicant will also be engaged in multidisciplinary discussions to determine the clinical impact of variants discovered in the analysis, and further refinement of conclusions during multidisciplinary genetics monthly meetings.

　　Fixed-term: The funds for this post are available until 31 January 2020 in the first instance.

　　To apply online for this vacancy and to view further information about the role, please visit:

　　http://www.jobs.cam.ac.uk/job/17382. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

　　Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

　　Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

　　Closing date for applications is the 29th May 2018, with the interview date being 5th June 2018.

　　Please quote reference RP15452 on your application and in any correspondence about this vacancy.

　　The University values diversity and is committed to equality of opportunity.

　　The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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