迈阿密大学米勒医学院西尔维斯特综合癌症中心（SCCC）癌症方向博士后招聘

Pioneer Award funded research in the laboratory of Dr. Ramin Shiekhattar, a leader in epigenetics and RNA biology fields, is centered on identifying mechanisms and factors involved in enhancer function and enhancer deregulation in pancreatic cancer and melanoma using novel tools and methods toward enhancer therapy in cancer. These will include dissecting the role of enhancer RNAs (eRNAs) and long noncoding RNAs (lncRNAs) in enhancer function and cancer progression. Successful applicants will work on projects aimed at identifying and verifying the function of enhancer regulatory proteins and other epigenetic factors, during pancreatic and skin cancer progression. The group is using state-of-the-art techniques and model systems to achieve these goals, including protein loss-of-function (shRNA, CRISPR/Cas9), proteomic analysis (mass-spectrometry), and global genomics and transcriptomics technologies (RNA-seq, ChIP-seq) in cancer cell lines and patient-derived xenograft tumor models. Qualifications We are looking for candidates with high impact publications (scientific impact of 8 or higher journals). We need motivated, ambitious candidates with a strong interest in epigenetics and cancer. In addition, the successful candidate should have: A PhD in Life Sciences Proven track record of publication in international journals. Previous experience in biochemistry, stem cell and/or cancer biology. Excellent written and oral communication skills. Fluency in English is compulsory. The wish to be part of a highly interactive and international group of scientists. Place of employment Our lab is located at the Sylvester Comprehensive Cancer Center (SCCC), University of Miami Miller School of Medicine (http://medgen.med.miami.edu/shiekhattar). We offer creative and stimulating working conditions in a dynamic and international research environment. We have weekly journal clubs, data clubs and seminars with invited speakers. Please send your CV to Teodora Gueorguieva at txg120@med.miami.edu