Postdoctoral researcher in Biochemistry / Molecular Biology : Brno, Czech Republic

We are offering a position of Postdoctoral researcher within the research team of Dr. Lukáš Kubala focused on evaluation of the molecular aspects of adenylyl cyclases at the International Clinical Research Center of St. Anne´s University Hospital in Brno (FNUSA – ICRC).

Project: Isoforms of adenylyl cyclases as new perspetive drug targets

Start Date: 1. November 2017

About FNUSA-ICRC
The International Clinical Research Center of St. Anne's University Hospital in Brno (FNUSA-ICRC), Czech Republic is a new-generation research center focusing on the pathogenesis of diseases, including finding new methods, technologies and medicaments for effective prevention, early diagnostics and individualized treatment.
We are a top Central European research center with more than 200 researchers, new technologies and experience in using EU grant support. We focus on research and development mainly in the fields of cardiovascular and neurological diseases. Our partners are world-class research centers and universities

Job Description:
Postdoctoral researcher
Expertise: Biochemistry and molecular biology
• Evaluation of the molecular aspects of selective modulation of adenylyl cyclases for potential pharmaceutical applications. 
• Enzymology of individual isoforms of human adenylyl cyclases. 
• Determination of enzyme kinetics and screening of specific activators and inhibitors using the recently developed screening methods suitable for detection of the enzymatic activity of all different membrane-bound human adenylyl cyclase isoforms in both membrane-based and cell-based set up.