美国国立卫生研究院生物信息学博士后职位

Postdoc or Senior Scientist Position in Bioinformatics and Genomics

Background
A postdoctoral or staff scientist position is available in bioinformatics at the laboratory of Genomics & Immunity at the National Institutes of Health in Bethesda, Maryland. The major goal of our laboratory is to unravel the molecular mechanisms driving early development and peripheral activation of B lymphocytes. In particular, we are interested in the processes that assemble, diversify, and provide effector functions to antibody receptors, namely V(D)J recombination, somatic hypermutation, and class switching. Another major interest of our laboratory is to understand how deregulation of these reactions leads to B cell tumorigenesis. To achieve these goals, we are combining molecular biology, genome editing, mouse genetics, genomics, microscopy and bioinformatic tools.

The candidate will perform essential data analysis of genome-wide experiments, including ChIP-Seq, RNA-Seq, ChIA-PET, GRO-Seq, and MNaseI-Seq. In addition, She/he will explore single molecule microscopy data to link real time protein dynamics to static genomic views. Our laboratory represents an exciting and highly diverse group of scientists from a wide range of backgrounds and biological training. Additional information can be found at http://casellaslab.github.io/index.html
Requirements

• A PhD in genetics, genomics, bioinformatics, or computer science
• Expertise in at least one programming language (e.g. Python, Perl, or R)
• Proficiency in Unix/Linux operating system
• Experience analyzing functional genomics experiments
• Ability to conduct independent research and work cooperatively with other scientists.