荷兰阿姆斯特丹大学理论振动旋光性研究博士后职位

Postdoctoral researcher Theoretical Vibrational Optical Activity : Amsterdam, Netherlands

Postdoctoral researcher Theoretical Vibrational Optical Activity The vibrational optical activity of chiral molecules provides an unique signature that can be used to determine the absolute conformation of a molecule. This is important as in many cases the precise chirality of molecules determines their chemical and biological activity. The current combination of experimental and computational techniques is so far only applicable to relatively small molecules and under nonresonant conditions.  In this project methods will be developed that are able to treat larger molecules and methods that can be applied for Resonance Enhanced Vibrational Circular Dichroism (RE-VCD). This will be done in a consortium together with the Theoretical Chemistry group at the VU University Amsterdam, and the companies Scientific Computing & Modelling N.V. (The Netherlands) and BioTools, Inc. (USA). The postdoctoral researcher will be appointed at the University of Amsterdam for a period of 3 years. He/she will  utilize novel computational approaches based on a subsystem DFT methodology to  speed up calculations and thereby bring a much larger range of molecular systems within reach. Furthermore, he/she will be involved in the development and implementation of computational methods able to compute Resonance Enhanced VCD spectra, as well developing a graphical user interface that will facilitate a fast and conclusive interpretation of VCD spectra.
 

Description

For this position the required background is a PhD degree in theoretical chemistry. Besides extensive experience in computing and interpreting Vibrational Optical Activity, the successful candidate should also have first-hand experience with writing codes in large quantum chemical program packages (e.g. ADF, Gaussian, etc.). He/she should also be willing to become familiar with the experimental aspects of obtaining VCD spectra. Experience with supervision of PhD students is desirable.
 

Benefits

The initial appointment will be on a temporary base for one year, with an extension of two years depending on the candidate’s performing. The salary will be in accordance with the University regulations for academic personnel, and will range from €2,476 to €3,908 (salary scale 10) gross per month. This is excl. 8% holiday allowance and 8,3% end of year bonus. The Collective Labour Agreement for Dutch Universities is applicable.2476 - 3908