美国俄克拉何马医学研究基金会遗传学和复杂疾病的表观遗传学博士后职位

We are seeking a Post-doctoral Fellow to lead investigative studies on the genetic and epigenetic mechanisms of autoimmune diseases. The laboratory is currently investigating the genetic and epigenetic mechanisms of autoimmune susceptibility genes involved in the ubiquitination pathway including TNFAIP3, TNIP1, UBE2L3 and several others. While the genetic associations in these genes are confirmed, the causal variants that are responsible for SLE susceptibility are unclear. In addition, the regulatory mechanisms that result in disordered expression of these genes in the context of disease are not known. We are therefore seeking a highly talented and motivated individual to join our NIH funded laboratory and to lead investigation into the genomic and epigenomic mechanisms that influence the expression and function of these genes in the context of autoimmunity.