美国芝加哥大学发展与疾病分化控制研究博士后职位招聘

　　美国芝加哥大学发展与疾病分化控制研究博士后职位招聘

　　Postdoctoral Scholar for the Study of Differentiation Control in Development and Disease

　　·         University of Chicago

　　·         Location: Chicago, IL

　　·         Job Number: 7062375

　　·         Posting Date: Nov 15, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　How do progenitor cells know when and where to differentiate? Are there common

　　molecular mechanisms that control differentiation in diverse lineages? How does

　　dysfunction of these molecular mechanisms contribute to diseases, including dysmorphologies, cancer, and adult organ degeneration? Can modulation of these pathways improve organ regeneration?

　　Applications are invited for postdoctoral positions for research and training in the

　　Moskowitz laboratory (http://moskowitzlab.uchicago.edu/index.html) at The University of

　　Chicago on the molecular mechanisms controlling differentiation timing. The successful candidate will join our NIH funded investigation of the genomic and molecular analysis of differentiation timing in diverse lineages (e.g.bioRxiv 736322; doi: https://doi.org/10.1101/736322). We are investigating a generalizable molecular mechanism underlying differentiation timing control, with implications for organ development, adult stem cell maintenance, organ regeneration, and cancer biology.

　　The laboratory integrates genomics, bioinformatics, molecular biology, mouse genetics, human genetics, and embryonic stem cell differentiations to investigate basic principles of developmental biology. The laboratory is affiliated with the Departments of Pediatrics, Pathology, and Human Genetics and the Institute for Genomics and Systems Biology (http://www.igsb.org) a the University of Chicago. We are affiliated with graduate programs in Development, Regeneration and Stem Cell Biology

　　(https://drsb.uchicago.edu) and Genetics, Genomics and Systems Biology

　　(https://ggsb.uchicago.edu). We are located in the Knapp Center at the University of Chicago.

　　Highly motivated candidates with a recent PhD in developmental biology, molecular

　　biology, genetics, pathology, cardiology or related field and with at least one first author

　　paper in an English language journal are encouraged to apply. Experience with

　　genomics, molecular biology, mouse genetics, and/or bioinformatics is sought;

　　molecular biology skills are essential. Please send a letter describing research

　　experience/interest, CV, and contact information for three references electronically

　　to: cpaez@peds.bsd.uchicago.edu.

　　Please address correspondence to:

　　Ivan Moskowitz, M.D., Ph.D.

　　Professor and Vice Chair for Research

　　Departments of Pediatrics and Pathology

　　The University of Chicago

　　900 East 57th Street, KCBD Room 5102

　　Chicago, Illinois 60637

　　Key words: Differentiation, Genetics, Genomics, gene regulatory network, Heart, Development, Developmental Biology, regeneration, degeneration, Congenital Heart Disease, Cardiac, morphogenesis, cardiology, organogenesis, molecular mechanism

　　The University of Chicago is an Affirmative Action/Equal Opportunity Employer.