密歇根州立大学分子生物物理学博士后招聘

　　招聘简介：

　　·密歇根州立大学

　　·地点：密歇根州东兰辛

　　职位描述

　　密歇根州立大学物理与天文学系的康斯托克实验室正在寻找一名博士后研究员，以便在实验室内立即提供有关极端体外单分子生物物理学研究进展的研究进展。

　　康斯托克实验室是一个新的实验室，其中充满了渴望突破基础生物分子机器测量和观察边界的科学家。我们设计并构建了新型光学捕获和荧光仪器，可实现单分子生物测量的新模式。理想的候选人最近将获得博士学位。在生物物理学，物理学，化学或生物化学或相关领域，已具备以下研究经验：1）使用和开发单分子实验技术的经验，包括光学镊子（最好是双阱高分辨率版本），单分子荧光，FRET， 2）湿实验室经验，包括新型核酸构建体合成的详细经验，包括基于DNA和RNA的构建体，以及这些构建体的标记和纯化，以及3）蛋白质分子马达的研究经验（例如，解旋酶，聚合酶等）和/或核酸或蛋白质折叠。成功的候选人还将展示在高度协作的研究环境中工作的能力以及指导实验室初级成员的潜力。

　　英文原文：

　　·         Michigan State University

　　·         Location: East Lansing, MI

　　Job Description

　　The Comstock Lab at Michigan State University in the Department of Physics and Astronomy is seeking a postdoctoral Research Associate for an immediately available position within the lab advancing research progress on topics of extreme in vitro single molecule biophysics.

　　The Comstock Lab is a new lab filled with scientists eager to push the boundaries of measurement and observation of fundamental biological molecular machines. We design and build novel optical trapping and fluorescence instrumentation that enable new modalities of single molecule biological measurement. The ideal candidate would have recently obtained a Ph.D. in Biophysics, Physics, Chemistry or Biochemistry or related fields and would already possess the following research experience: 1) experience using and developing single molecule experimental techniques including optical tweezers (preferably dual-trap high-resolution versions), single molecule fluorescence, FRET, etc. 2) wet lab experience including detailed experience with novel nucleic acid construct synthesis, including DNA- and RNA-based constructs, as well as labeling and purification of such constructs, and 3) research experience with protein molecular motors (e.g., helicases, polymerases etc.) and/or nucleic acid or protein folding. The successful candidate will also demonstrate the ability to work within a highly collaborative research environment and the potential to mentor junior members of the lab.

　　Contact Information:

　　Matt Comstock

　　mjcomsto@msu.edu

　　Physics and Astronomy

　　567 Wilson Road, Room 4238

　　East Lansing,Michigan

　　United States

　　Tel: 5178845645