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美国纽约大学医学中心NYU Langone Medical Center 博士后职位
文章来源:知识人网整理       更新时间:2019年04月15日

  招聘简介:

  纽约大学医学院的Holger Knaut团队寻求具有细胞生物学、荧光显微镜或生物物理学经验的高动机、注重细节和热情的博士或医学博士毕业生,以探索与使用定量imagi的活动物在形态发生过程中调节细胞行为相关的项目。遗传学和计算建模。

  我们小组的目标是破译形态发生过程中动态细胞行为的物理、分子和细胞原理。我们希望揭示这些原理将提供对正常细胞动力学如何促进发育和体内平衡以及为什么扰动会导致缺陷和疾病的理解。

  我们实验室用来理解动态细胞行为的当前模型是神经元聚集成团(Lewellis等人细胞生物学杂志。2013),《感觉器官的组织运动》(Venkiteswaran G等人细胞。2013年,Wang J等人发育细胞。以及斑马鱼冠状动脉网络的形成(Nagelberg D等人当代生物学。2015)。为了研究这些过程,我们通常与其他实验室合作,使用经典遗传学、基因组工程、先进的荧光显微镜和计算模型。

  英文原文:

  The group of Holger Knaut at NYU School of Medicine seeks highly motivated, detail orientated, and passionate Ph.D. or M.D. graduates with experience in cell biology, fluorescence microscopy or biophysics to explore projects related to the regulation of cellular behaviors during morphogenesis in the context of live animals using quantitative imaging, genetics and computational modeling.

  The goal of our group is to decipher the physical, molecular and cellular principles underlying dynamic cell behaviors during morphogenesis. We hope that uncovering these principles will provide an understanding of how normal cell dynamics contributes to development and homeostasis and why perturbations cause defects and disease.

  Current models our lab uses to understand dynamic cell behavior are the assembly of neurons into clusters (Lewellis S et al. Journal of Cell Biology. 2013), the tissue movement of sensory organs (Venkiteswaran G et al. Cell. 2013, Wang J et al. Developmental Cell. 2018) and the formation of the coronary artery network in zebrafish (Nagelberg D et al. Current Biology. 2015). To interrogate these processes we use classical genetics, genome engineering, advanced fluorescence microscopy and computational modeling, often in collaboration with other laboratories.

  Our group is located in the Skirball Institute of the NYU School of Medicine in midtown Manhattan (New York City). The Skirball Institute is a premier institution for biomedical research. The institute focuses boldly on basic research. It also provides excellent core facilities and a supportive environment for interactions between its labs and the clinical disciplines at NYU Langone Medical Center. With a strong awareness that most medical breakthroughs originate in basic research, the medical center has allocated considerable resources in developing a state-of-the-art, modern, interdisciplinary research unit right in the center of the medical school environment.

  Candidates should have a recent MD, PhD or MD/PhD degree and a strong background in cell biology, fluorescent microscopy or biophysics. Although not essential, candidates with experience in the use of animal models are encouraged to apply. Please send a cover letter explaining relevant work experience and interests, a CV, and the contact information of three references to Holger Knaut at holger.knaut@med.nyu.edu.

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