美国City of Hope细胞生物学博士后招聘

　　招聘简介：

　　城市的希望

　　位置：Duarte，CA

　　职位编号：7056920

　　posting日期：4月11日，2019

　　工作描述

　　《城贝克曼研究所希望看着一talented postdoctoral研究员。急性淋巴细胞白血病患者骨髓细胞的发展。《白血病耐药细胞可以成为两个药物治疗获得支持，因为他们对他们的生长和存活的间充质干细胞从在这个环境。本实验室研究的分子和机制，是负责这类药物耐药性的发展。

　　主要责任包括：

　　在这个位置上我们都是特别感兴趣的人和一个专业的博士学位和在细胞生物学研究院的两个机制programmed溶酶体的细胞死亡。我们的工作与白血病细胞共培养的细胞与基质细胞，细胞成像，逆转录病毒或慢病毒转导，CRISPR / CAS基因敲除小鼠，用流式细胞术检测鸭。关于谁是感兴趣的学术生涯是在下面的路径，是自我激励和享受大学生物系统的复杂性是encouraged特别适用。

　　英文原文：

　　City of Hope

　　Location: Duarte, CA

　　Job Number: 7056920

　　Posting Date: Apr 11, 2019

　　Job Description

　　The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Acute lymphoblastic leukemia develops in the bone marrow. The leukemia cells can become resistant to drug treatment because they obtain support for their growth and survival from stromal cells in this environment. This lab studies the molecules and mechanisms that are responsible for this type of drug resistance development.

　　Key Responsibilities include:

　　For this position we are particularly interested in someone with a PhD and expertise in cell biology to study mechanisms of lysosomal programmed cell death. We work with leukemia in tissue co-culture with stromal cells, cell imaging, retroviral or lentiviral transduction, Cas/CRISPR knockout, FACS, and mice. Candidates who are interested in following an academic career path, are self-motivated and enjoy the complexity of biological systems are especially encouraged to apply.

　　Basic education, experience and skills required for consideration:

　　Ph.D. in cell biology or related field.

　　Experience in working with hematopoietic cells in tissue culture, imaging cells.

　　Preferred education experience and skills:

　　Expertise in glycobiology is an advantage but not required.

　　Additional Information:

　　The location of our lab at the Monrovia Campus of the Beckman Research Institute within the Department of Systems Biology provides many opportunities to interact with others who study leukemias.

　　Our lab also has ongoing collaborations in the area of glycobiology with scientists at the Institute for Glycomics, Griffith University, Australia.

　　Please include an updated CV, a 1-page cover letter describing your current position, your reasons for applying and contact details of three recent referees as a single PDF.

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