美国安德森肿瘤中心单细胞基因组学方向博士后职位招聘

　　Postdoc Positions in Single Cell Genomics - Data Scientist and Cancer Biologist

　　MD Anderson Cancer Center

　　NAVIN LAB JOB DESCRIPTIONS

　　Single Cell Data Scientist – Postdoc

　　Single Cell Cancer Biologist – Postdoc

　　Summary

　　The Navin laboratory (www.navinlab.com) at the MD Anderson Cancer Center in Houston TX (www.mdanderson.org) has two open postdoctoral fellow positions. We are looking for bright, motivated individuals that are interested in working on cutting-edge research projects that will use single cell sequencing technologies with spatial resolution to study cancer evolution, including invasion, metastasis and therapy resistance. Our interdisciplinary team combines experimental biology, technology development and computational biology to address major questions in cancer genomics. We focus mainly on the genomic analysis of human tumor tissues and collaborate closely with clinical groups at MD Anderson. More information on each position is listed below:

　　Computational Biologist – Postdoctoral Fellow

　　The ideal candidate for this position will have a Ph.D. in bioinformatics, computational biology or data science. The person should be highly proficient in scripting languages (perl, python) and statistical languages such as R, particularly in the use of packages such as bioconducter or biopython. Additional programming skills in Java or C++ will be useful. The applicant should have extensive experience working in unix environments with computing clusters/servers. A strong background and course work in statistics, computer science and data science is also required. The individual will work on developing new computational approaches for analyzing large-scale single cell sequencing datasets that are generated in our laboratory from single cell DNA, RNA or ATAC-seq platforms. This data will be used to study the evolution of tumor cells and cell types in the microenvironment. The individual will work closely with technologists and experimental biologists to develop new single cell sequencing technologies, including methods with spatial resolution. A background in working with imaging and spatial data will be very beneficial for integrating single cell genomic and spatial datasets.

　　Cancer Biologist – Postdoctoral Fellow

　　The ideal candidate for this position will have a Ph.D. in cancer biology, molecular biology or genomics. The individual will be proficient in molecular biology skills, including standard cancer assays, cell culture, PCR, qPCR and next-generation sequencing methods. The ideal candidate will be highly motivated, independant and excited about developing and applying new technologies to study cancer evolution. Background in ecology or evolution, or cancer evolution would be beneficial but is not required. The postdoc will work on research projects that involve understanding cancer evolution in response to therapy using multiple single cell DNA, RNA and ATAC sequencing technologies, as well as spatially-resolved genomic approaches and other genomic & molecular biology approaches.

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