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    美国休斯敦卫理公会研究所神经外科博士后职位招聘
    文章来源:知识人网整理       更新时间:2018年11月15日

      Postdoctoral Fellow -Neurosurgery -Rostomily

      Houston Methodist

      Houston, TX

      The Rostomily lab at the Houston Methodist Research Institute and Houston Methodist Department of Neurosurgery has a post-doctoral fellowship position immediately available to pursue development of a microfluidic based pre-clinical screening platform for drug sensitivity testing of patient derived tumor samples. This project is NIH funded and the candidate will also receive support from the PIs Dunn Chair in brain tumor biology. The project is a collaboration with Drs Albert Folch (microfluidics, bioengineering) and Ray Monnat (genome sciences, pathology) at the University of Washington. The candidate will contribute in one or more of the following areas according to interest and expertise:

      1) characterization and drug response testing of PDX and patient derived slice cultures on microfluidic devices (generated at UW). This project involves profiling of slice culture immunophenotypes including stromal immune elements and adaptation of the model for potential testing of immunotherapies as well as genomically informed targeted therapies and conventional cyto/genotoxic drugs and radiation.

      2) development of advanced automated real-time readouts for cell responses to treatments compatible with the existing or modified versions of the mircrofluidic device

      3) generation of alternative 3D tissue engineered platforms from primary tumor tissues for drug testing on the microfluidic device

      4) validation of predictive power of the platform by in vivo testing and comparison with alternative pre-clinical screening techniques.

      PATIENT AGE GROUP SERVED

      Not applicable

      DUTIES AND RESPONSIBILITIES

      Develops research methods and performs research activities. (EF)

      Documents research results and writes reports of results for presentation and/or publication in professional journals and other publications. (EF)

      Assists in maintaining the functionality and operations of the Principal Investigator¿s laboratory. (EF)

      Demonstrates the components of the I CARE values. (EF)

      Follows all safety rules while on the job. Reports accidents promptly and corrects minor safety hazards. Communicates with peers and management regarding any hazards identified in the workplace. (EF)

      Performs other duties as assigned by the Principal Investigator.

      EDUCATION REQUIREMENTS

      M.D. or Ph.D required

      EXPERIENCE REQUIREMENTS

      Experience requirements will vary depending on the field of research.

      Postdoctoral Fellow 0 -no Postdoctoral experience required

      Postdoctoral Fellow 1 -one year of Postdoctoral experience

      Postdoctoral Fellow 2 -two years of Postdoctoral experience

      Postdoctoral Fellow 3 -three years of Postdoctoral experience

      Postdoctoral Fellow 4 -four years of Postdoctoral experience

      CERTIFICATES, LICENSES AND REGISTRATIONS REQUIRED

      Not applicable

      SPECIAL KNOWLEDGE, SKILLS AND ABILITIES REQUIRED

      Experience in biomedical research required

      PHYSICAL REQUIREMENTS

      Research laboratory environment

      WORKING ENVIRONMENT

      Research laboratory environment

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