- The University of Texas M. D. Anderson Cancer Center
- Location: Houston, TX
- Job Number: 7051993
- Posting Date: Jul 15, 2018
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Job Description
Two postdoctoral fellow positions are available to investigate the structure and function of mammalian ion channel signaling complexes using techniques of protein chemistry, mass spectrometry-based proteomics, electrophysiological patch-clamp recording, and transgenic human cells and rodent animal models. The currently investigated ion channels include the large conductance calcium-activated potassium (BK) channels, the N-methyl-D-aspartate (NMDA) receptors, and the two-pore channels (TPCs). We are particularly interested in: 1) exploratory identification of novel ion channel auxiliary or regulatory proteins; 2) investigation of the biochemical and biophysical mechanisms underlying the channel modulation by new auxiliary or regulatory proteins; and 3) exploration of physiological and pathological roles of newly identified ion channel auxiliary or regulatory proteins.
Lab website: https://www.mdanderson.org/research/departments-labs-institutes/labs/yan-laboratory.html
Applicants should have a PhD degree obtained within three years. Regardless of prior research field, please feel free to apply if you consider yourself highly motivated and creative. Prior experience in patch-clamp recording, mass spectrometry (label-free & isobaric labeling quantification), or protein structural biology will be preferred but not required.
Applicants should send curriculum vitae, a short statement of research interest and qualifications, and names and addresses of three references to: Dr. Jiusheng Yan (Email: jyan1@mdanderson.org), Division of Anesthesiology and Critical Care, University of Texas MD Anderson Cancer Center, Houston, TX 77030.
M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.
