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比利时鲁汶表观遗传重编程细胞命运中的博士后位置
文章来源:知识人网       更新时间:2018年06月11日

The Pasque group is studying epigenetics, cell fate reprogramming and pluripotency. We are interested in understanding how cell identity and gene expression is reprogrammed after transcription factor expression and how epigenetic silencing contributes to health and disease. More info: www.kuleuven.be/pasquelab

Our project will define the mechanisms that regulate mammalian cell fate reprogramming and pluripotency by exploiting recent advances in single cell omics and CRISPR. We aim to unravel the epigenetic and gene regulatory mechanisms that control the maintenance versus reversal of cellular identity. You will define how different subpopulations of cells evolve during cellular reprogramming to pluripotency and study key regulators of cellular heterogeneity.
You will collaborate with other groups within and outside of KU Leuven.

Responsibilities

The research will focus on the discovery of the molecular pathways influencing cell state transitions during reprogramming somatic cells to induced pluripotent stem cells. To achieve this, the candidate will apply and develop novel tools that will enable dissecting those pathways.

Profile

Candidates must have obtained a PhD degree.
Candidates should have at least 1 first author publications. 2 first author publications is an plus.
General knowledge of deep sequencing data analysis is highly desirable.

A very good command of spoken and written English is required and sufficient for communication within and outside the laboratory since Leuven is very international.

Offer

The position is funded for 2 years with possibility of extension.
The project is funded by the Flanders Research Foundation Odysseus Programme (FWO) and the KU Leuven.
Access to state-of-the-art infrastructure and competitive salary.
The position is available immediately.
We will encourage you to apply for independent funding and mentor you to achieve your career goals (our first postdoc successfully secured an assistant professor position).

Interested?

Your application file must include: – Cover letter containing statement of motivation – CV (summarizing education, positions and academic work, scientific publications) – Name and contact details of 3 referees (including email addresses and phone numbers) For more information please contact Prof. dr. Vincent Pasque, vincent.pasque@kuleuven.be.
You can apply for this job no later than June 30, 2018 via the online application tool
KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.

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