美国玛里兰州Henry M Jackson Foundation博士后职位

HJF is seeking a highly motivated Post-doctoral Fellow for the Uniformed Services University (USU) Center for Prostate Disease Research (CPDR) located in Rockville, Maryland. The Post-doctoral Fellow will have demonstrated experience and strong publication record in cancer biology, cancer drug screen and development, including cell culture and in vivo models of cancer. HJF provides programmatic support services to CPDR. The incumbent will work as a member of the multi-disciplinary group under the over all directions of the Scientific Director and designee.

The USU - CPDR is an Integrated Translational Prostate Disease Research Center with a comprehensive inter-disciplinary research program to study prostate diseases in the tri-service military health care system with key collaborating partners at the WRNMMC and the JPC.  The CPDR was established in 1991 by the United States Congress and has developed comprehensive bio-specimen banks and multi-center patient database.  The collaborative expertise and resources of the clinical and basic science researchers of the Center has led to ground-breaking discoveries which are improving early detection, prognosis and the treatments for prostate diseases. These achievements have propelled its reputation as one of the leading prostate disease research centers in the nation.

RESPONSBILITIES

• Performs and manages state-of-the-art cancer drug screen and cancer biology experiments that includes cell culture, in vivo models of prostate cancer, molecular biology and biochemical approaches in support of drug development in the context of prostate cancer. Manages and meets the time lines of tasks as defined by the Scientific Director.
• Develops high impact scientific publications and that will support major grant applications.
• Technologies may include but not limited to in vivo models or prostate cancer, cell culture models, required for therapeutic molecule screening and development,  kinase assays, preparation of expression vectors, protein purification, RNA sequencing, base line bioinformatics of gene expression analysis, immunobloting, quantitative PCR, FISH and immuno-histochemistry, (including frozen and FFPE tissue, blood/serum and urine specimens).
• Performs specialized prostate cancer research projects focusing on therapeutic developments in prostate cancer. Works as a member of the multidisciplinary team of cancer biologists, medical-and bio-informaticians, pathologists, urologists, and epidemiologists.
• Uses state-of-the-art bioinformatics in the context of prostate cancer drug discovery and development.
• Designs, develops, executes and implements scientific research. Maintains detailed electronic records of experiments under CPDR standard operation procedures (SOPs).
• Develops innovative assays that can improve the treatment of prostate cancer.
• Develops and/or acquires new technologies from other laboratories as needed for specific projects.
• Strictly adheres to laboratory and institutional SOPs established by CPDR/USU, JPC, WRNMMC and HJF.
• Prepares project progress reports, study protocols for in vivo prostate cancer models, scientific presentations and manuscripts for publication. Coordinates all regulatory requirements for the assigned research projects.
• Provides collaborative assistance to other research scientists that require the incumbent's expertise.
• Performs other research support activities as required by the Scientific Director or designee.