Post-Doctoral Fellow – Genetic Therapies for Retinal Diseases : Boston, MA, United States

Post-Doctoral Fellow – Genetic Therapies

• for Retinal Diseases*
  Ocular Genomics Institute, Mass Eye and Ear and Harvard Medical School

We are seeking a talented postdoctoral fellow to join our team to study the use of genetic therapies for the treatment of inherited retinal degenerations (IRDs). IRDs are important causes of vision loss that affect people of all ages. These disorders cause vision loss via dysfunction and death of the photoreceptor and retinal pigment epithelial cells of the retina. Gene augmentation therapies for several specific genetic forms of IRD show promise in clinical trials. There is also interest in applying CRISPR/Cas9 mediated genome editing techniques to treat IRDs, especially those caused by mutations in large genes, or by dominant gain-of-function mutations. We are looking for a postdoc to help develop additional genetic therapies, including gene augmentation therapies andCRISPR/Cas9 mediated genome editing to treat several genetic forms of retinal degeneration. The project is supported by NIH and private funding.

Qualified candidates should have strong molecular and cellular biologic skills, and be able to work independently as well as in a group environment. This position offers an excellent opportunity to learn and apply skills in genetics, molecular biology, gene augmentation therapies, CRISPR/Cas9 genome editing, and evaluation of animal models of disease. Experience in one or more of these areas is preferred.