Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

A highly motivated Post-Doctoral research fellow is sought to carry out research in the laboratory of Dr. Denise Galloway at Fred Hutchinson Cancer Research Center in Seattle, WA. Recent postdocs or graduate students at the end of their training program, who are eligible for participation in NIH-funded training grants and fellowships, are especially encouraged to apply.

About the Galloway Lab:

The primary focus of the Galloway lab (http://research.fhcrc.org/galloway/en.html) is the role that small DNA viruses, such as human papillomavirus (HPV), and Merkel Cell polyomavirus (MCPyV) play in cancer. We have taken a broad approach including mechanistic studies into how viral oncoproteins contribute to neoplasia and molecular epidemiologic studies into the natural history of viral infections and risk factors associated with cancer development. We are currently studying 1) the long-term memory to HPV vaccination or infection; 2) mechanisms by which high-risk HPVs perturb the response to DNA damage; and 3) the functions of a newly identified protein, ALTO, in the MCPyV life cycle.

Responsibilities:

The fellow will focus on HPV biology, investigating the mechanisms by which the E6 and E7 oncoproteins perturb the response to DNA damage. In addition to performing research the post-doc will have the opportunity to present their work at local and other meetings.

Qualifications

The successful candidate must have a recent PhD in a relevant biological field with a demonstrated track record of productive research and be able to work both independently and as part of a laboratory team. The candidate must also have a strong background in essential molecular and cellular biology techniques, as well as extensive experience with cell/ tissue culture techniques. Experience with genome analysis, RNAi technology, and developmental virology are highly desirable.

Salary is based on the NIH scale and the funding for this position is for three to four years, depending on productivity. Please note that at least two letters of recommendation will be requested as part of the screening process. Please include a cover letter detailing your interest and suitability for this position with your application.