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美国西奈医学院肿瘤的异质性,转移和耐药性方向博士后

2016年08月17日

来源：知识人网整理

摘要：

Become a Cedars-Sinai Employee

Requisition #:	24719
Working Title:	Postdoctoral Scientist
Business Entity:	AHR - Academic Human Resources
Cost Center # - Cost Center Name:	0801094 - Home Dept-Fine
City:	Los Angeles
Job Category:	Academic Affairs/Research Institute
Job Specialty:	Research
Position Type:	Regular-F/T
Shift Length:	8hr
Hours:	8am-5pm
Days:	Monday - Friday
Shift Type:	Day
Weekends:	As Needed
Job Posting:	A position is open for a Postdoctoral Scientist to join a creative laboratory focusing on tumor heterogeneity, metastasis and drug resistance. The laboratory has recently developed a strategy that enables the tracking of individual cells within heterogeneous cancer cell populations throughout disease progression. Current work is focused on optimizing this method to make it more readily applicable to a variety of in vitro and in vivo disease models. The successful candidate will work with the Principal Investigator, a team of PhD students and laboratory technicians to perform this optimization before applying it to elucidate molecular drivers of disease progression and drug resistance. Later studies will involve genomic profiling (RNAseq, Exom -Capture, Copy number-variation) of single cells and clonal cell populations. The work will also involve the use of next generation shRNA and CRISPR/Cas9 libraries to perform loss-of-function and gain-of-function screens. ESSENTIAL JOB DUTIES AND RESPONSIBILITIES: • Design and implement high-throughput molecular cloning procedures • Design and implement molecular and cellular biology experiments • Design and implement animal studies • Analyze, interpret and summarize experimental data • Prepare manuscripts for publication • Attend scientific meetings and present research findings EEO / AA / F / M / Veteran / Disabled
Qualification Requirements/Preferences: Education Certifications/Licensure Experience Physical Abilities	EDUCATIONAL REQUIREMENTS: PhD in area directly related to field of research specialization. EXPERIENCE: Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. Preferred demonstrated scientific creativity and rigor by publishing their PhD work in reputable scientific journals. Preferred experience in tumor-immunology. Preferred experience with molecular cloning, cell culture, virus production, DNA/RNA extraction, next-generation sequencing technologies mouse injections, and tissue extraction. PHYSICAL DEMANDS: (e.g. lifting standing, walking) The candidate must be able to use pipetmen. There will be some long periods of standing.

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