University of Dundee - MRC Protein Phosphorylation and Ubiquitylation Unit

Location: Dundee

Salary: £30,434 to £37,394

Hours: Full Time

Contract Type: Contract / Temporary 

Placed on: 10th September 2015

Closes: 25th October 2015

Job Ref: SLSC0017

We wish to recruit an enthusiastic and highly motivated post-doctoral research fellow for the laboratory of Dr Matthias Trost. The applicant will be working in a project studying a novel cell signalling pathway in macrophages in disease-relevant models.

 

Our lab uses state-of-the-art proteomics, cell biology and biochemistry technologies and applies them to important biological questions. We have in the recent past published important papers for the understanding of molecular mechanisms in macrophage biology and disease models (Trost et al, 2009, Immunity; Lai et al, 2015, EMBO Journal; Guo et al, submitted). Moreover, we have developed exciting new mass spectrometry technologies that helped advance the ubiquitylation and phosphorylation fields (Ritorto et al, Nature Communications, 2014; Ritorto et al, J Proteome Res, 2013) and we have several new unpublished technologies.

 

Applicants should have a recent PhD in a relevant scientific discipline, such as biology, immunology, biochemistry or analytical chemistry and one first authored publication in an internationally recognised peer-reviewed journal. An understanding of macrophage biology, cell culture, cell signalling as well as cell biological and biochemical techniques would be an advantage. Knowledge and experience of working with mass spectrometry systems, quantitative proteomics approaches and data analysis is not essential and training in these techniques will be provided. In addition, the candidate should be able to work independently and thrive in a multi-disciplinary research environment. Strong interpersonal and communication skills are essential as is the ability to work as part of a team. The position is until March 2018 in the first instance and is available immediately. However, candidates wishing to start at any time up to March 2016 will be considered.