Postdoctoral Position - Nogales Lab : Berkeley, CA, United States

Job Description

The Nogales lab, a Howard Hughes Medical Institute laboratory located at the University of California Berkeley, is seeking a highly creative, motivated, and skilled Postdoctoral Associate in the area of Structural Biophysics to study yeast septins assembly, interaction with lipids, and cellular ultrastructure. The successful candidate will apply his/her knowledge in membrane biophysics and cellular ultrastructure determination to unravel the mechanisms of septins cellular functions during cytokinesis involving their diffusion barrier and scaffolding roles.

Principal Responsibilities:

• Expression and purification of septins for in vitro studies
• Fluorescence studies of septin interaction with GUVs
• Electron tomography studies of dividing yeast cells to characterize septin ultrastructure throughout the cell cycle

Preferred Qualifications:

• Strong background and publication record in membrane biophysics and/or cellular ultrastructure characterization
• Experience with membrane interacting proteins, GUVs and/or quantitative fluorescence microscopy
• Experience with cellular electron microscopy (embedding and sectioning) and tomography, and/or general biochemistry/molecular biology techniques.