美国明尼苏达大学蛋白质工程博士后职位

We are looking for candidates who are highly motivated to employ in vitro selection and directed evolution to create de novo proteins, or tailor existing enzymes to a variety of useful applications. We have established a general method to create enzymes from scratch – enzymes that have not been found in nature. Our approach enables us to search for enzymes in libraries of trillions of proteins variants in a single experiment.

• One objective of our research is to create enzymes as ‘designer catalysts’ for biomedical applications. We are also studying our new enzymes in detail and evolve them further to elucidate basic principles of biocatalysis and protein evolution.

• Another objective of our work is to tackle questions related to the origin of life. Specifically, we are investigating the origin and early evolution of functional proteins and the genetic code.

The applicant should have a Ph.D., expertise in molecular biology and biochemistry, a strong publication record, excellent communication skills, and enthusiasm and motivation to do science in a collaborative environment. The candidate’s potential and ambition to obtain independent funding is highly valued.

Please send a letter that specifically details why you would want to work with us and how your scientific interests and research experience would fit with our team. Send this letter, together with your CV, list of publications and the names of three references to Burckhard Seelig (seelig@umn.edu). The position is available immediately.

Our lab is part of the interdisciplinary BioTechnology Institute at the University of Minnesota – one of the largest research universities in the US. We are located in the heart of the vibrant Minneapolis-Saint Paul area, home to 3.4 Million people and urban center of the ‘Land of Ten Thousand Lakes’.