加拿大药物研究与发展中心药理学和毒理学博士后职位

Post-Doctoral Fellow, Pharmacology and Toxicology : Vancouver, Canada

The Centre for Drug Research and Development (CDRD) is Canada’s fully-integrated national drug development and commercialization centre, providing expertise and infrastructure to enable researchers from leading health research institutions to advance promising early-stage drug candidates. Our mandate is to de-risk discoveries stemming from publicly-funded health research and transform them into viable investment opportunities for the private sector — thus successfully bridging the commercialization gap between academia and industry, and translating research discoveries into new therapies for patients. Canada’s Networks of Centres of Excellence Program has recognized CDRD as a Centre of Excellence for Commercialization and Research (CECR).

Summary

Reporting to the Division Head, Pharmacology & Toxicology, the Postdoctoral fellow will work within and across the CDRD divisions and participate in inter-disciplinary drug research and development project teams that encompass expertise from target identification, screening, synthetic & analytical chemistry, lead optimization, formulation, ADME/T and in vivo PoC. The individual in this role will be working within teams to provide scientific expertise to design and conduct critical experiments to advance the technologies through early pre-clinical development and provide technology development spans small molecule and biologic therapeutics.

Responsibilities

• Primary bench research will include the in vitro and in vivo characterization of drug candidates including assessment of on-target and off-target activity, ADME liabilities as well as in vivo properties including pharmacokinetics and bio distribution, tolerability and efficacy in relevant disease models.
• Responsible for advancement of projects, including scientific planning and experimentation, data reporting, team communication and meeting milestones and schedules.
• Strong adherence to research ethics guidelines and protocols
• Other related duties as assigned.

Qualifications and Experience

• Recent completion, or completion within the next 3 months, of a PhD in Pharmaceutical Sciences or a related biological discipline.
• Experience in one or more of the following areas:
• Development, characterization and conduct of in vivo models of important human diseases.
• Pharmacokinetic and/or bioanalytical analysis.
• In vitro, in vivo or ex vivo assessment of drug safety.
• Mechanism of action/pharmacodynamics
• Preferred candidates will be flexible, with a determination to further their skills in multiple areas.
• Willingness to contribute to and work in a team environment is required.
• A good publication record, with experience related to drug research.
• Excellent oral and written communication skills.
• Working knowledge of Microsoft Office.