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    美国分子肿瘤学研究所博士后研究员职位
    文章来源:知识人网整理       更新时间:2014年12月22日

    Post Doctoral Research Fellow

    Req Number:550753

    Department::Molecular Oncology Research Institute (MORI)
    Schedule:Full-Time Regular
    Shift:Day shift
    Grade:88
    Hours:8:30A-4P
    Job Details:

    • MD or PhD required
    • We have an opening for a Post-doctoral Fellow to work in the field of Inflammation and Protease Signaling in the Center of Hemostasis and Thrombosis at Tufts Medical Center.

      Under the direction of Dr. Athan Kuliopulos, the candidate will have the opportunity to conduct state-of-art research in models of sepsis and inflammation.

      The candidate will work primarily on a project involving protease-G protein coupled receptor signaling in the cells of the blood vessel wall, employing their skills in signal transduction assays and cell and molecular biology, in addition to animal models.

      There are three areas of research that the postdoc will be involved in. One is to determine how metalloproteases regulate endothelial barrier function and sepsis. The second is to determine the effect of MMP1 haplotypes on sepsis outcomes in patient samples. Thirdly, cell-penetrating pepducin technology, pioneered in the Kuliopulos lab, will be employed in various models of sepsis and patient samples.

      The postdoc will spearhead the design and execution of experiments, as well as their interpretation.

      REQUIREMENTS:

      The position requires excellent quantitative and analytical skills and experience with tissue culture techniques and biochemistry/si

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