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美国阿尔伯特·爱因斯坦医学研究院分子和生化机制重组抗体可变区研究博士后职位

2014年10月09日
来源:知识人网整理
摘要:
A POSTDOCTORAL FELLOWSHIP is available to study the molecular and biochemical mechanisms of antibody variable region hypermutation and class switch recombination. We use tissue culture and mouse models that can be manipulated genetically and biochemically to study the role of activation induced deaminase and error prone mismatch repair in the targeting of somatic hypermutation. Some of these studies have been extended to examine the role of activation induced deaminase in the progression of Chronic Lymphocytic Leukemia