当前位置:知识人网 >> 国外博士后招聘 >> 正文内容

英国诺威奇食品研究所招聘食品安全相关博士后
文章来源:知识人整理       更新时间:2014年09月22日

Postdoctoral Scientist – Gut Health and Food Safety : Norwich, United Kingdom

Applications are invited for a Postdoctoral Scientist to work in the Gut Health and Food Safety Department at the Institute of Food Research in Norwich.

The successful applicant will work on a research project entitled “A multidisciplinary approach to studying crypt-villus homeostasis and regeneration in the intestinal epithelium” (http://decryptingvillus.ifr.ac.uk/), funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

This project is a joint venture between the Institute of Food Research, the University of East Anglia and the Wolfson Centre for Mathematical Biology at the University of Oxford. The appointee will work with Prof Alastair Watson, Prof Simon Carding and Dr Carmen Pin, who are based at the Institute of Food Research and at the University of East Anglia in Norwich, and with Prof Philip Maini and Prof Helen Byrne, based at the University of Oxford

The intestinal epithelium forms the first barrier between the gut lumen and the body. It has a complex architecture, with invaginations into the intestinal wall, called crypts, located between finger-like projections into the lumen, called villi. Intestinal stem cells located at the base of each crypt proliferate and give rise to epithelial cells, which migrate to the tips of the neighbouring villi, from where they are shed into the gut lumen. In the healthy intestine, the dimensions and cell number in crypts and villi remain remarkably constant during adult life. This requires a tight coordination of cell proliferation, migration and shedding. Dysregulation of these processes contributes to intestinal pathologies such as tumourigenesis, ulcerative inflammatory processes and coeliac disease.

The aim of this project is to understand the precise coordination between villi and crypts during the continuous renewal of the epithelium lining the small intestine and how this equilibrium is recovered after perturbations. The appointee will be a cell/epithelial biologist responsible for conducting work using experimental model systems to develop and test hypotheses on the mechanism of regulation between cell proliferation, cell migration and cell shedding along the crypt-villus axis and of the regulation between crypts and villi populations. The Postdoctoral Scientist will investigate the impact of several epithelial induction protocols on the organization of the tissue by in vitro culturing methods, immunostaining, microscopy and molecular techniques.

The Postdoctoral Scientist will be required to disseminate research via peer reviewed journal publications, presentations, workshops and conferences and communication with diverse stakeholders including scientists, funding agency staff, and industry personnel.

Salary on appointment will be within the range £29, 500 to £36, 060 per annum depending on qualifications and experience. The position is available for 2 years in the first instance. …

扫一扫知识人网官方微信订阅号,关注更多学术资讯、博士后招聘信息。
国外博士后、访问学者申请免费专业评估,专业顾问在线答疑解惑。

快速申请国外博士后(免费评估)


点击这里快速申请国外博士后

点击这里快速申请国外访问学者

知识人网是专职国外博士后访问学者申请的服务机构,获评“北京诚信服务示范单位”。
自2004年起,累计十余年申请经验,以大量名校申请成功案例、及全球三万余所院校导师资源为基石,提供优质的申请咨询服务。
400电话:400-060-0581,欢迎您随时来电咨询!