美国辛辛那提儿童医学中心囊性纤维化研究博士后职位

A postdoctoral Research Fellow position is available in Dr AP Naren's lab (http://www.cincinnatichildrens.org/bio/n/ap-naren/ ) in the Division of Pulmonary Medicine at Cincinnati Children's Hospital Medical Center. Dr Naren's lab is interested in identifying interactions between CFTR and its binding partners and defining how spatiotemporal regulation of CFTR-containing macromolecular complexes in the apical compartment of polarized epithelial cells lining the secretory epithelia regulates overall fluid secretion. The research involves several complimentary approaches in understanding Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) using in vitro (tissue culture) and in vivo (CF-knock out mouse model) systems. Studies will involve crypt isolation and 3D culture of organoids, two electrode voltage clamping (TEVC), Ussing Chamber, Iodide efflux measurements, FRET-imaging, Single Particle Tracking (SPT), molecular cloning, protein purification and protein binding assays. We are looking for a highly motivated newly graduated researcher.
To apply online go to: http://www.cincinnatichildrens.org/careers/apply/default.htm and search for requisition 72733. Please upload your cv, cover letter including a statement of research interests, and contact information for 3 references.

CCHMC is an Equal Opportunity Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, genetic information, physical or mental disability, military or veteran status, sexual orientation, or other protected status in accordance with applicable federal, state, and local laws and regulations….