瑞典乌普萨拉大学进化生物学中心两年期博士后职位招聘

Postdoctoral Researcher in in pinniped population genomics : Uppsala, Sweden

A 2-year postdoctoral researcher position is available in the group of Jochen Wolf at the Evolutionary Biology Centre in Uppsala, Sweden.

Background. We are a young, growing research group that applies an integrative approach to study evolutionary processes in natural populations. Major research themes include the evolutionary processes and genetic mechanisms underlying species divergence (e.g. Wolf et al. 2010, Ellegren et al. 2012, Poelstra et al. in press) and genome evolution (e.g. Mugal et al. 2014). Using large-scale genomic approaches, we characterize divergence across populations and (sub-)species differing in the degree of reproductive isolation and assess its relationship to functional phenotypic divergence. Empirical systems currently include birds (swallows and corvids), Pelophylax frogs and marine mammals (pinnipeds and killer whales).

This post-doc position is broadly embedded in a research program on Galapagos sea lions (Zalophus wollebaeki) that Prof. Fritz Trillmich and Dr. Jochen Wolf started 12 years ago (http://www.uni-bielefeld.de/biologie/vhf/FT/sealion.html). Using whole genome re-sequencing data from more than 100 individuals across the entire species range and populations from its Californian sister species (Zalophus californianus) the project addresses key evolutionary processes such as the genetic basis of fitness, adaptation, and speciation. A key feature of the system is the presence of different ecotypes in an essentially sympatric setup (cf. Wolf et al. 2008, Shafer & Wolf 2013). We closely co-operate with Dr. Joe Hoffman from Bielefeld University (http://www.uni-bielefeld.de/biologie/vhf/JH/) working with Antarctic fur seal populations (Hoffman et al. 2014) opening a comparative axis to the project.

Qualifications. The successful applicant holds a PhD degree, has a thorough background in population genetics and/or comparative genomics and is experienced in handling large genome-wide data sets. Population geneticists with a more theoretical background are also encouraged to apply.

The environment. The Evolutionary Biology Centre (http://www.ebc.uu.se/) is one of the world’s leading research institutions in evolutionary biology. It is part of Uppsala University which has been ranked first place among all European Universities in the subject of biology (CHE European ranking) and bridges a broad variety of disciplines. The scientific environment with numerous seminars, journal clubs and social activities offer excellent possibilities for contacts and collaborations. A graduate school currently directed by Jochen Wolf provides a framework for courses and high-profile seminars broadly reflecting our research interests (http://www.ebc.uu.se/education/postgrad/gradschool/Seminars). Our lab is part of the Department of Evolutionary Biology (http://www.ebc.uu.se/Research/IEG/evbiol/), an active environment addressing fundamental evolutionary questions with a wide range of different approaches. As a member of the Science for Life Laboratory (http://www.scilifelab.se/) we have access to high performance computing resources (https://www.uppmax.uu.se/uppnex), excellent lab facilities and extended bioinformatic infrastructure (http://www.scilifelab.se/platforms). The lab is situated in the student town of Uppsala, that offers rich opportunities in cultural and outdoor activities. Sweden's capital Stockholm is less than an hour's train ride away.

How to apply. Applications should include a CV, a statement of motivation and the contact details of at least two references. Use the following link to access the application form: http://www2.personalavd.uu.se/jobb/appform.php?lang=en&case=UFV-PA%202014/1605

The positions remains open until filled. Starting date is flexible. For more information contact jochen.wolf@ebc.uu.se or see http://www.ebc.uu.se/Research/IEG/evbiol/research/Wolf/.

Literature.

Poelstra JW, Vijay N, Bossu CM et al. Wolf JBW (in press) The genomic landscape underlying phenotypic integrity in the face of gene flow in crows. Science

Mugal CF, Wolf JBW, Kaj I (2014)Why Time Matters: Codon Evolution and the Temporal Dynamics of dN/dS, Mol Biol Evol 31, 212–231.

Ellegren H, Smeds L, Burri R et al. Wolf JBW (2012) The genomic landscape of species divergence in Ficedula flycatchers. Nature, 491, 756–760.

Shafer ABA, Wolf JBW (2013) Widespread evidence for incipient ecological speciation: a meta-analysis of isolation-by-ecology. Ecol Lett, 16, 940–950.

Hoffman JI, Simpson F, David P et al. (2014) High-throughput sequencing reveals inbreeding depression in a natural population. PNAS, 201318945.

Wolf JBW, Harrod C, Brunner S et al. (2008) Tracing early stages of species differentiation: Ecological, morphological and genetic divergence of Galapagos sea lion populations. BMC Evol Biol, 8, 150.

Wolf, JBW, Lindell J, Backstrom N (2010)Speciation genetics: current status and evolving approaches, Philos Trans R Soc Lond B 365, 1717–1733. …