美国橡树岭国家实验室微生物生态生理学招聘博士后助理研究员

The Biosciences Division of Oak Ridge National Laboratory (ORNL) is seeking a microbiologist to work on a multi-institutional project. The successful post-doctoral fellow will apply, utilize and develop novel methods toward understanding the interactions between bacterial community structure and function, and metals (including heavy metals and radionuclides). This will include the determining and characterizing the biotransformation of these metals, the resultant biogeochemistry, and their effect on the microbial community populations. Whole community microbial ecology will be coupled to cutting edge model community construction and assessment in efforts to close the lab to field gap in our knowledge base. Particular metals of interest include Hg, U, and Cr. Existing techniques will include controlled cultivation, ICP-MS analysis of Hg species, U(VI) quantification, GC, GC-MS, IC, HPLC, de-novo population and isolate genome sequencing, genomics, transcriptomics, proteomics as well as meta-omics, (RT)-PCR, q(RT)-PCR, genetic manipulation, and bioinformatics.

Major Duties / Responsibilities

The successful candidate will join a multi-disciplinary team of investigators who apply advanced and integrated techniques to understand the physiology and ecology of microorganisms in support of US Dept. of Energy missions in remediation and systems biology. There will be opportunities to be involved in areas of this, and perhaps other projects, which will utilize several approaches. These range from basic biogeochemistry to metabolic modeling to cutting edge genomics in order to develop new ways of understanding the role of microorganisms in metal and radionuclide biotransformations.

Qualifications

A Ph.D. in biochemistry, microbiology, molecular biology, genetics, bioinformatics or related field is required. Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment.

The following skills are required for this position:

- Aerobic and Anaerobic cultivation; experience with fermentation/controlled cultivation desired
- Design and execution of biochemical assays to investigate enzyme-catalyzed processes
- Molecular biology techniques including PCR, qPCR, RT-PCR
- Experience with DNA and mRNA sequencing bioinformatics programs is highly desired
- Effective writing and presentation skills, demonstrated by a strong publication record from previous research
- Desire to work both independently and collaboratively as part of a multidisciplinary team
Applicants cannot have received the most recent degree more than five years prior to the date of application and must complete all degree requirements before starting their appointment.
This position is a full-time assignment for 24 months, contingent on successful performance and continued funding.