瑞典阿斯利康制药公司细胞和分子生物学,生物化学和生理学博士后职位

At AstraZeneca We are seeking talented scientists who are interested in pursuing an academic-style Postdoc in a global pharmaceutical setting and contributing to AstraZeneca’s commitment to delivering innovative medicines. This newly expanded internal pharmaceutical Postdoctoral research program spans multiple therapeutic areas and a wide range of scientific disciplines.

Your comprehensive training program includes a focus on drug discovery and development, as well as exposure to existing local and global Postdoctoral Research communities within AstraZeneca. Postdoctoral scientists will have the opportunity to conduct independent cutting-edge work in state-of-the-art laboratories while teaming with other AstraZeneca scientists.

Each Postdoctoral scientist will also be able to collaborate with a leading academic advisor who will provide further support and guidance.

Additionally, the Postdoc will be encouraged to attend and present at international scientific conferences and publish high-profile papers.

Accountabilities/Responsibilities

• Expand cell lines like Min6cl4 and EndoC and culture islets from primary human tissue.

• Design and perform functional studies like for example GSIS, proliferation and apoptosis assays.

• Design and perform mechanistic pharmacology and molecular biology studies in vitro related to relevant signaling pathways.

• Design and perform in vivo pharmacology experiments in mice transplanted with human islets.

• Perform histological evaluations of in vivo studies.

• Interact and collaborate with scientists at AstraZeneca and our academic collaborator while at the same time drive the project independently

• Communicate results and novel findings both internally and at external conferences

• Publish scientific papers in high ranked journals

Minimum Requirements – Education and Experience

• A PhD in one of the following areas: Cell and molecular biology, Biochemistry or Physiology

• Good cell and molecular biology lab skills (e.g. cell culture, imaging, cell sorting, transfection, western blotting, qPCR)

• Solid experience in biology relevant to diabetes and/or receptor pharmacology

• Scientific track record in islet biology and specifically in beta-cell function

• Experience in performing functional studies (e.g. GSIS, proliferation and apoptosis assays)

• Experience in histology and imaging

• A strong scientific track record, as evidenced by published papers in peer-reviewed journals.

• Ability to work independently but collaboratively and generate hypotheses based on experimental data in a focused manner.

Other Skills & Capabilities

• Strong passion and commitment to science, and ability to collaborate and work independently with a clear focus on delivery.

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, or protected veteran status and will not be discriminated against on the basis of disability….